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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP8L3
All Species:
6.97
Human Site:
Y180
Identified Species:
15.33
UniProt:
Q5GJ75
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5GJ75
NP_997264.2
292
32659
Y180
A
I
K
I
G
I
L
Y
R
N
N
Q
F
S
Q
Chimpanzee
Pan troglodytes
XP_523074
439
49535
Y327
A
I
K
I
G
I
L
Y
R
N
N
Q
F
S
Q
Rhesus Macaque
Macaca mulatta
XP_001082153
204
23341
T118
K
L
N
Q
T
A
M
T
I
V
S
F
Y
E
V
Dog
Lupus familis
XP_544677
213
24592
I128
L
N
Q
T
A
M
T
I
V
S
F
Y
E
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3TBL6
204
23224
T118
K
L
N
Q
T
A
M
T
M
V
S
F
Y
E
V
Rat
Rattus norvegicus
Q6AYJ8
184
20732
M99
Q
K
L
R
Q
G
A
M
T
A
L
S
F
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516626
259
28726
L163
E
L
R
T
V
D
R
L
R
K
K
L
N
Q
T
Chicken
Gallus gallus
Q5ZJU8
186
21516
A101
V
H
T
L
A
M
T
A
V
S
F
H
Q
I
D
Frog
Xenopus laevis
Q6DFE2
202
23269
A117
L
N
Q
T
C
M
T
A
V
S
F
F
E
V
E
Zebra Danio
Brachydanio rerio
Q7T3D0
202
23182
V117
M
N
Q
A
A
M
T
V
V
S
F
Y
E
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KVH9
188
21368
I103
F
Q
N
T
Q
L
S
I
I
S
F
Y
E
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61
69.5
66.4
N.A.
63.3
33.2
N.A.
57.1
41.4
54.4
48.2
N.A.
27
N.A.
N.A.
N.A.
Protein Similarity:
100
63.3
69.8
69.8
N.A.
66
49.6
N.A.
68.4
54.1
63.3
60.2
N.A.
42.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
0
6.6
N.A.
6.6
0
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
26.6
13.3
N.A.
20
20
26.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
28
19
10
19
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
19
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
37
19
37
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
46
28
28
0
0
% F
% Gly:
0
0
0
0
19
10
0
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
19
0
19
0
19
0
19
19
0
0
0
0
10
0
% I
% Lys:
19
10
19
0
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
19
28
10
10
0
10
19
10
0
0
10
10
0
0
0
% L
% Met:
10
0
0
0
0
37
19
10
10
0
0
0
0
0
0
% M
% Asn:
0
28
28
0
0
0
0
0
0
19
19
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
28
19
19
0
0
0
0
0
0
19
10
10
19
% Q
% Arg:
0
0
10
10
0
0
10
0
28
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
46
19
10
0
19
0
% S
% Thr:
0
0
10
37
19
0
37
19
10
0
0
0
0
0
10
% T
% Val:
10
0
0
0
10
0
0
10
37
19
0
0
0
37
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
0
28
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _