KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HERC4
All Species:
26.67
Human Site:
S374
Identified Species:
58.67
UniProt:
Q5GLZ8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5GLZ8
NP_056416.2
1057
118563
S374
I
F
S
G
G
D
Q
S
F
S
H
Y
S
S
P
Chimpanzee
Pan troglodytes
XP_001167753
1057
118665
S374
I
F
S
G
G
D
Q
S
F
S
H
Y
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001087608
1057
118587
S374
I
F
S
G
G
D
Q
S
F
S
H
Y
S
N
P
Dog
Lupus familis
XP_849808
1057
118464
S374
I
F
S
G
G
D
Q
S
F
S
H
Y
S
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAV2
1057
118393
S374
I
F
S
G
G
D
Q
S
F
S
H
Y
S
S
P
Rat
Rattus norvegicus
Q5PQN1
1057
118521
S374
I
F
S
G
G
D
Q
S
F
S
H
Y
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508293
996
112121
D366
V
E
I
A
N
E
I
D
G
T
F
S
S
A
G
Chicken
Gallus gallus
XP_001231234
1056
118760
S374
I
F
S
G
G
D
Q
S
F
A
H
Y
F
Y
P
Frog
Xenopus laevis
NP_001086738
897
100543
H305
Q
I
A
C
G
R
Q
H
T
L
A
F
V
P
S
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Q174
R
T
A
S
G
R
I
Q
Y
L
N
H
I
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
I301
T
K
T
S
Q
Q
L
I
Q
S
L
R
R
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
98.1
N.A.
96.7
96.9
N.A.
86.8
88.1
64.9
22.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
99.3
N.A.
98.7
98.7
N.A.
91.1
94.5
75
37.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
6.6
80
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
86.6
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
0
0
0
0
0
10
10
0
0
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
64
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
64
0
0
0
0
0
0
64
0
10
10
10
0
0
% F
% Gly:
0
0
0
64
82
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
64
10
0
0
0
% H
% Ile:
64
10
10
0
0
0
19
10
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
19
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
10
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
73
% P
% Gln:
10
0
0
0
10
10
73
10
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
19
0
0
0
0
0
10
10
0
10
% R
% Ser:
0
0
64
19
0
0
0
64
0
64
0
10
64
37
10
% S
% Thr:
10
10
10
0
0
0
0
0
10
10
0
0
0
19
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
64
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _