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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGG All Species: 14.24
Human Site: S641 Identified Species: 31.33
UniProt: Q5H8A4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5H8A4 NP_001120650.1 983 108173 S641 D K G H G S P S T S E V L R G
Chimpanzee Pan troglodytes XP_001138024 983 108092 S641 D K G H G S P S T S E V L R G
Rhesus Macaque Macaca mulatta XP_001112555 975 107376 S633 D K G H R S P S A S Q G L R G
Dog Lupus familis XP_536282 983 108886 T642 H G V S R S L T S L D T L R G
Cat Felis silvestris
Mouse Mus musculus Q9JJI6 1093 119138 L681 C V G A L V A L L V V V R L W
Rat Rattus norvegicus XP_223731 978 107708 S636 D T A G K R A S L L E A H R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424872 1014 111957 S669 S K L G K A A S S A E F V K G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921696 463 51503 I127 K L M E M D D I I K K I H A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121027 772 88869 W437 H Q T W Y F Y W V T V L I F Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795273 987 108841 V652 R A W N Q T G V E W A N L P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40367 830 94833 M495 I I V R W F I M M A C V R S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.4 84 N.A. 25.2 80.2 N.A. N.A. 66.6 N.A. 31.6 N.A. N.A. 30.4 N.A. 37.8
Protein Similarity: 100 99.6 96.6 89.5 N.A. 40.4 87.2 N.A. N.A. 78.9 N.A. 38.8 N.A. N.A. 47.6 N.A. 54
P-Site Identity: 100 100 73.3 26.6 N.A. 13.3 26.6 N.A. N.A. 26.6 N.A. 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 80 46.6 N.A. 13.3 26.6 N.A. N.A. 60 N.A. 13.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 10 28 0 10 19 10 10 0 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 37 0 0 0 0 10 10 0 0 0 10 0 0 0 10 % D
% Glu: 0 0 0 10 0 0 0 0 10 0 37 0 0 0 0 % E
% Phe: 0 0 0 0 0 19 0 0 0 0 0 10 0 10 0 % F
% Gly: 0 10 37 19 19 0 10 0 0 0 0 10 0 0 46 % G
% His: 19 0 0 28 0 0 0 0 0 0 0 0 19 0 0 % H
% Ile: 10 10 0 0 0 0 10 10 10 0 0 10 10 0 10 % I
% Lys: 10 37 0 0 19 0 0 0 0 10 10 0 0 10 0 % K
% Leu: 0 10 10 0 10 0 10 10 19 19 0 10 46 10 0 % L
% Met: 0 0 10 0 10 0 0 10 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 28 0 0 0 0 0 0 10 0 % P
% Gln: 0 10 0 0 10 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 10 0 0 10 19 10 0 0 0 0 0 0 19 46 0 % R
% Ser: 10 0 0 10 0 37 0 46 19 28 0 0 0 10 19 % S
% Thr: 0 10 10 0 0 10 0 10 19 10 0 10 0 0 0 % T
% Val: 0 10 19 0 0 10 0 10 10 10 19 37 10 0 0 % V
% Trp: 0 0 10 10 10 0 0 10 0 10 0 0 0 0 10 % W
% Tyr: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _