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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL13A All Species: 11.82
Human Site: S218 Identified Species: 16.25
UniProt: Q5H913 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5H913 NP_001155963 297 33799 S218 G E R C S S H S F S T R T G M
Chimpanzee Pan troglodytes XP_521175 308 35266 S218 G E R C S S H S F S T R T G M
Rhesus Macaque Macaca mulatta XP_001090836 297 33776 S218 G E R C S S H S L S T R T G M
Dog Lupus familis XP_545056 443 50183 K307 D G R P L K H K V E H E Q I E
Cat Felis silvestris
Mouse Mus musculus Q9D416 372 43445 Q236 R V R H S N R Q H F D K R Q H
Rat Rattus norvegicus Q6AXT3 395 45449 S226 G E R C S S D S L S T R G V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514970 442 50454 Q308 K S N P E Q E Q M E T Q S H T
Chicken Gallus gallus XP_416642 425 48393 N263 I A A V I S E N E K Q I E K E
Frog Xenopus laevis Q8QHI3 182 20390 E106 R F E E T G Q E L A E L L D E
Zebra Danio Brachydanio rerio Q8JHI3 407 46548 E207 R V Q K D T A E Q K A Q E E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06849 184 20816 V108 S C G Q E L Q V L L Q E E R L
Honey Bee Apis mellifera XP_394559 184 21013 K108 D C K I E L Y K L L Q E E R L
Nematode Worm Caenorhab. elegans O45379 184 20752 L108 F D E M N I E L G E L L D E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310807 185 21192 L109 C K M E L D N L L K E E R L S
Maize Zea mays NP_001149177 185 21154 L109 C R A E L H N L L K E E R L V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPX1 185 21059 L109 C K M E L D N L L K E E R L A
Baker's Yeast Sacchar. cerevisiae P40994 183 20678 L107 M E E A K E E L Y S I I G E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 95.6 25.7 N.A. 47.8 48 N.A. 26.7 28.2 22.5 27 N.A. 24.2 24.5 21.5 N.A.
Protein Similarity: 100 93.8 97.3 41.3 N.A. 62 59.4 N.A. 40.2 44 37.3 44.2 N.A. 36.7 38.3 35.6 N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 13.3 66.6 N.A. 6.6 6.6 0 0 N.A. 0 0 0 N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 26.6 66.6 N.A. 20 13.3 13.3 20 N.A. 6.6 20 13.3 N.A.
Percent
Protein Identity: 25.2 24.2 N.A. 25.5 21.5 N.A.
Protein Similarity: 40.4 40.4 N.A. 41 37 N.A.
P-Site Identity: 0 0 N.A. 0 13.3 N.A.
P-Site Similarity: 13.3 13.3 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 12 6 0 0 6 0 0 6 6 0 0 0 6 % A
% Cys: 18 12 0 24 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 6 0 0 6 12 6 0 0 0 6 0 6 6 0 % D
% Glu: 0 30 18 24 18 6 24 12 6 18 24 36 24 18 24 % E
% Phe: 6 6 0 0 0 0 0 0 12 6 0 0 0 0 0 % F
% Gly: 24 6 6 0 0 6 0 0 6 0 0 0 12 18 6 % G
% His: 0 0 0 6 0 6 24 0 6 0 6 0 0 6 6 % H
% Ile: 6 0 0 6 6 6 0 0 0 0 6 12 0 6 0 % I
% Lys: 6 12 6 6 6 6 0 12 0 30 0 6 0 6 6 % K
% Leu: 0 0 0 0 24 12 0 30 48 12 6 12 6 18 12 % L
% Met: 6 0 12 6 0 0 0 0 6 0 0 0 0 0 18 % M
% Asn: 0 0 6 0 6 6 18 6 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 6 6 0 6 12 12 6 0 18 12 6 6 6 % Q
% Arg: 18 6 36 0 0 0 6 0 0 0 0 24 24 12 0 % R
% Ser: 6 6 0 0 30 30 0 24 0 30 0 0 6 0 6 % S
% Thr: 0 0 0 0 6 6 0 0 0 0 30 0 18 0 6 % T
% Val: 0 12 0 6 0 0 0 6 6 0 0 0 0 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _