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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL13A All Species: 10.91
Human Site: S258 Identified Species: 15
UniProt: Q5H913 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5H913 NP_001155963 297 33799 S258 A I K S I L Y S L R G S R R V
Chimpanzee Pan troglodytes XP_521175 308 35266 S258 A I K S I L Y S L R G S R R V
Rhesus Macaque Macaca mulatta XP_001090836 297 33776 S258 A I K P V L Y S L R G S R R V
Dog Lupus familis XP_545056 443 50183 D347 T Q Q L E N E D E T D Q R S S
Cat Felis silvestris
Mouse Mus musculus Q9D416 372 43445 P276 Q R S L D A R P L K P I L Q K
Rat Rattus norvegicus Q6AXT3 395 45449 F266 H F E K R Q H F E S R Q H L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514970 442 50454 Q348 N E D E I D Q Q S S D C L D P
Chicken Gallus gallus XP_416642 425 48393 S303 A Q Q L S T N S S Q K T N D S
Frog Xenopus laevis Q8QHI3 182 20390 H146 I A E G L N L H T I R D R V W
Zebra Danio Brachydanio rerio Q8JHI3 407 46548 E247 R E G R T L K E E E L D D V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06849 184 20816 T148 I L H L E D I T T H H W L V A
Honey Bee Apis mellifera XP_394559 184 21013 K148 I L E L P S I K T H H W Q I Y
Nematode Worm Caenorhab. elegans O45379 184 20752 L148 T R K L N L D L L R D R T W H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310807 185 21192 K149 L N L E N M D K T R H W K I V
Maize Zea mays NP_001149177 185 21154 R149 L N L E V M D R S R H W K I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPX1 185 21059 K149 L N L E S M D K S R H W K I V
Baker's Yeast Sacchar. cerevisiae P40994 183 20678 K147 S D F L E L E K N L K N Q P W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 95.6 25.7 N.A. 47.8 48 N.A. 26.7 28.2 22.5 27 N.A. 24.2 24.5 21.5 N.A.
Protein Similarity: 100 93.8 97.3 41.3 N.A. 62 59.4 N.A. 40.2 44 37.3 44.2 N.A. 36.7 38.3 35.6 N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 6.6 0 N.A. 6.6 13.3 6.6 6.6 N.A. 0 0 26.6 N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 20 20 N.A. 6.6 33.3 20 6.6 N.A. 13.3 20 26.6 N.A.
Percent
Protein Identity: 25.2 24.2 N.A. 25.5 21.5 N.A.
Protein Similarity: 40.4 40.4 N.A. 41 37 N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 33.3 N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 6 0 0 0 6 0 0 0 0 0 0 0 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % C
% Asp: 0 6 6 0 6 12 24 6 0 0 18 12 6 12 0 % D
% Glu: 0 12 18 24 18 0 12 6 18 6 0 0 0 0 0 % E
% Phe: 0 6 6 0 0 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 0 6 6 0 0 0 0 0 0 18 0 0 0 0 % G
% His: 6 0 6 0 0 0 6 6 0 12 30 0 6 0 6 % H
% Ile: 18 18 0 0 18 0 12 0 0 6 0 6 0 24 6 % I
% Lys: 0 0 24 6 0 0 6 24 0 6 12 0 18 0 6 % K
% Leu: 18 12 18 42 6 36 6 6 30 6 6 0 18 6 0 % L
% Met: 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 18 0 0 12 12 6 0 6 0 0 6 6 0 6 % N
% Pro: 0 0 0 6 6 0 0 6 0 0 6 0 0 6 6 % P
% Gln: 6 12 12 0 0 6 6 6 0 6 0 12 12 6 0 % Q
% Arg: 6 12 0 6 6 0 6 6 0 42 12 6 30 18 0 % R
% Ser: 6 0 6 12 12 6 0 24 24 12 0 18 0 6 12 % S
% Thr: 12 0 0 0 6 6 0 6 24 6 0 6 6 0 0 % T
% Val: 0 0 0 0 12 0 0 0 0 0 0 0 0 18 36 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 30 0 6 12 % W
% Tyr: 0 0 0 0 0 0 18 0 0 0 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _