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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL13A All Species: 10.61
Human Site: T208 Identified Species: 14.58
UniProt: Q5H913 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5H913 NP_001155963 297 33799 T208 I S I S K N N T G S G E R C S
Chimpanzee Pan troglodytes XP_521175 308 35266 T208 I S I S K N N T G S G E R C S
Rhesus Macaque Macaca mulatta XP_001090836 297 33776 T208 I S I S K N N T G S G E R C S
Dog Lupus familis XP_545056 443 50183 K297 K R R Q N M E K D S D G R P L
Cat Felis silvestris
Mouse Mus musculus Q9D416 372 43445 L226 E R C L S D S L P N R V R H S
Rat Rattus norvegicus Q6AXT3 395 45449 R216 I S S S K N I R G C G E R C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514970 442 50454 T298 M E S G R D D T P L K S N P E
Chicken Gallus gallus XP_416642 425 48393 F253 P G N S E N P F Q P I A A V I
Frog Xenopus laevis Q8QHI3 182 20390 D96 I Y V I D S A D R K R F E E T
Zebra Danio Brachydanio rerio Q8JHI3 407 46548 I197 I A K D Y E A I S E R V Q K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06849 184 20816 R98 V D S A D R M R L E S C G Q E
Honey Bee Apis mellifera XP_394559 184 21013 R98 I D S A D R R R L E D C K I E
Nematode Worm Caenorhab. elegans O45379 184 20752 K98 F V I D S N D K K R F D E M N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310807 185 21192 L99 D S S D L R R L D D C K M E L
Maize Zea mays NP_001149177 185 21154 L99 D S S D I R R L D D C R A E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPX1 185 21059 L99 D S S D L R R L D D C K M E L
Baker's Yeast Sacchar. cerevisiae P40994 183 20678 R97 F V I D S S A R N R M E E A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 95.6 25.7 N.A. 47.8 48 N.A. 26.7 28.2 22.5 27 N.A. 24.2 24.5 21.5 N.A.
Protein Similarity: 100 93.8 97.3 41.3 N.A. 62 59.4 N.A. 40.2 44 37.3 44.2 N.A. 36.7 38.3 35.6 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 13.3 73.3 N.A. 6.6 13.3 6.6 6.6 N.A. 0 6.6 13.3 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 33.3 73.3 N.A. 33.3 20 26.6 20 N.A. 13.3 20 33.3 N.A.
Percent
Protein Identity: 25.2 24.2 N.A. 25.5 21.5 N.A.
Protein Similarity: 40.4 40.4 N.A. 41 37 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: 13.3 6.6 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 12 0 0 18 0 0 0 0 6 12 6 0 % A
% Cys: 0 0 6 0 0 0 0 0 0 6 18 12 0 24 0 % C
% Asp: 18 12 0 36 18 12 12 6 24 18 12 6 0 0 6 % D
% Glu: 6 6 0 0 6 6 6 0 0 18 0 30 18 24 18 % E
% Phe: 12 0 0 0 0 0 0 6 0 0 6 6 0 0 0 % F
% Gly: 0 6 0 6 0 0 0 0 24 0 24 6 6 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 42 0 30 6 6 0 6 6 0 0 6 0 0 6 6 % I
% Lys: 6 0 6 0 24 0 0 12 6 6 6 12 6 6 6 % K
% Leu: 0 0 0 6 12 0 0 24 12 6 0 0 0 0 24 % L
% Met: 6 0 0 0 0 6 6 0 0 0 6 0 12 6 0 % M
% Asn: 0 0 6 0 6 36 18 0 6 6 0 0 6 0 6 % N
% Pro: 6 0 0 0 0 0 6 0 12 6 0 0 0 12 0 % P
% Gln: 0 0 0 6 0 0 0 0 6 0 0 0 6 6 0 % Q
% Arg: 0 12 6 0 6 30 24 24 6 12 18 6 36 0 0 % R
% Ser: 0 42 42 30 18 12 6 0 6 24 6 6 0 0 30 % S
% Thr: 0 0 0 0 0 0 0 24 0 0 0 0 0 0 6 % T
% Val: 6 12 6 0 0 0 0 0 0 0 0 12 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 6 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _