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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL13A All Species: 13.03
Human Site: T274 Identified Species: 17.92
UniProt: Q5H913 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5H913 NP_001155963 297 33799 T274 W H P L R M K T T L V K K N R
Chimpanzee Pan troglodytes XP_521175 308 35266 T274 W H P L R M K T T L V K K N R
Rhesus Macaque Macaca mulatta XP_001090836 297 33776 T274 W H P L R M K T T L V K K N R
Dog Lupus familis XP_545056 443 50183 T363 S D N S K K K T K K L R I K R
Cat Felis silvestris
Mouse Mus musculus Q9D416 372 43445 K292 G F R I R P K K N M S V T F A
Rat Rattus norvegicus Q6AXT3 395 45449 L282 R S L D A R P L K P I L Q K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514970 442 50454 K364 N S K K K T K K L R L K R S H
Chicken Gallus gallus XP_416642 425 48393 T319 L E T C N S T T A Q H F Q H E
Frog Xenopus laevis Q8QHI3 182 20390 T162 I Q S C S A L T G Q G V Q D G
Zebra Danio Brachydanio rerio Q8JHI3 407 46548 N263 F N P F Q P I N N V L T E N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06849 184 20816 K164 V S A V T G E K L L S S M D W
Honey Bee Apis mellifera XP_394559 184 21013 N164 C S A I T G E N L V E G I N W
Nematode Worm Caenorhab. elegans O45379 184 20752 N164 Q A C S A L K N E G I N D G I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310807 185 21192 G165 C S A Y T G E G L L E G F D W
Maize Zea mays NP_001149177 185 21154 G165 C S A Y T G E G L L E G F D W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPX1 185 21059 G165 C S A Y T G E G L L E G F D W
Baker's Yeast Sacchar. cerevisiae P40994 183 20678 S163 V I G S N A L S G Q G L V E G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 95.6 25.7 N.A. 47.8 48 N.A. 26.7 28.2 22.5 27 N.A. 24.2 24.5 21.5 N.A.
Protein Similarity: 100 93.8 97.3 41.3 N.A. 62 59.4 N.A. 40.2 44 37.3 44.2 N.A. 36.7 38.3 35.6 N.A.
P-Site Identity: 100 100 100 20 N.A. 13.3 0 N.A. 13.3 6.6 6.6 13.3 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 40 N.A. 26.6 13.3 N.A. 40 20 20 60 N.A. 26.6 26.6 20 N.A.
Percent
Protein Identity: 25.2 24.2 N.A. 25.5 21.5 N.A.
Protein Similarity: 40.4 40.4 N.A. 41 37 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: 20 20 N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 30 0 12 12 0 0 6 0 0 0 0 0 6 % A
% Cys: 24 0 6 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 6 0 0 0 0 0 0 0 0 6 30 6 % D
% Glu: 0 6 0 0 0 0 30 0 6 0 24 0 6 6 6 % E
% Phe: 6 6 0 6 0 0 0 0 0 0 0 6 18 6 0 % F
% Gly: 6 0 6 0 0 30 0 18 12 6 12 24 0 6 12 % G
% His: 0 18 0 0 0 0 0 0 0 0 6 0 0 6 6 % H
% Ile: 6 6 0 12 0 0 6 0 0 0 12 0 12 0 6 % I
% Lys: 0 0 6 6 12 6 42 18 12 6 0 24 18 12 0 % K
% Leu: 6 0 6 18 0 6 12 6 36 42 18 12 0 0 0 % L
% Met: 0 0 0 0 0 18 0 0 0 6 0 0 6 0 0 % M
% Asn: 6 6 6 0 12 0 0 18 12 0 0 6 0 30 0 % N
% Pro: 0 0 24 0 0 12 6 0 0 6 0 0 0 0 0 % P
% Gln: 6 6 0 0 6 0 0 0 0 18 0 0 18 0 6 % Q
% Arg: 6 0 6 0 24 6 0 0 0 6 0 6 6 0 24 % R
% Ser: 6 42 6 18 6 6 0 6 0 0 12 6 0 6 0 % S
% Thr: 0 0 6 0 30 6 6 36 18 0 0 6 6 0 0 % T
% Val: 12 0 0 6 0 0 0 0 0 12 18 12 6 0 0 % V
% Trp: 18 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % W
% Tyr: 0 0 0 18 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _