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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 10.3
Human Site: Y295 Identified Species: 15.11
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 Y295 T T V P G Y T Y Q G H G L T P
Chimpanzee Pan troglodytes XP_001153855 674 74011 I236 H S S P K E N I G L N V F L S
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 Y295 T T V P G Y T Y Q G H G L T P
Dog Lupus familis XP_545496 695 74019 Y257 P A A L V P G Y N G A S K K A
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 Y295 T T V P G Y T Y Q G H G L T P
Rat Rattus norvegicus Q6GX84 677 74178 L239 F P K T S T G L N M F L S N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 P292 D P G F S D R P S V P A V R G
Chicken Gallus gallus Q5ZK92 613 66247 Q175 C E R A R R L Q S K M M T N L
Frog Xenopus laevis Q6DDU8 655 72133 N216 N T S L M Q R N E V K A P T T
Zebra Danio Brachydanio rerio Q503S1 736 79183 N291 P I A P T P L N G S S A N T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530 C85 N S V F E P E C R G F Y E S C
Honey Bee Apis mellifera XP_625184 585 66969 S147 H F E E H K S S F S I N N S V
Nematode Worm Caenorhab. elegans O16299 594 66169 C156 T K I R D K I C D I V D P T N
Sea Urchin Strong. purpuratus XP_783737 603 65189 N165 G Q T G N M S N N N N Q E E P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 P85 R R A F K E A P T G R R A A S
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 N386 Q I S K L M K N N H V P Y L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 6.6 100 13.3 N.A. 100 6.6 N.A. 0 0 13.3 13.3 N.A. 13.3 0 13.3 6.6
P-Site Similarity: 100 20 100 13.3 N.A. 100 6.6 N.A. 6.6 0 20 13.3 N.A. 33.3 13.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 19 7 0 0 7 0 0 0 7 19 7 7 7 % A
% Cys: 7 0 0 0 0 0 0 13 0 0 0 0 0 0 7 % C
% Asp: 7 0 0 0 7 7 0 0 7 0 0 7 0 0 0 % D
% Glu: 0 7 7 7 7 13 7 0 7 0 0 0 13 7 0 % E
% Phe: 7 7 0 19 0 0 0 0 7 0 13 0 7 0 0 % F
% Gly: 7 0 7 7 19 0 13 0 13 38 0 19 0 0 7 % G
% His: 13 0 0 0 7 0 0 0 0 7 19 0 0 0 0 % H
% Ile: 0 13 7 0 0 0 7 7 0 7 7 0 0 0 0 % I
% Lys: 0 7 7 7 13 13 7 0 0 7 7 0 7 7 7 % K
% Leu: 0 0 0 13 7 0 13 7 0 7 0 7 19 13 13 % L
% Met: 0 0 0 0 7 13 0 0 0 7 7 7 0 0 0 % M
% Asn: 13 0 0 0 7 0 7 25 25 7 13 7 13 13 7 % N
% Pro: 13 13 0 32 0 19 0 13 0 0 7 7 13 0 32 % P
% Gln: 7 7 0 0 0 7 0 7 19 0 0 7 0 0 0 % Q
% Arg: 7 7 7 7 7 7 13 0 7 0 7 7 0 7 0 % R
% Ser: 0 13 19 0 13 0 13 7 13 13 7 7 7 13 13 % S
% Thr: 25 25 7 7 7 7 19 0 7 0 0 0 7 38 7 % T
% Val: 0 0 25 0 7 0 0 0 0 13 13 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 19 0 25 0 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _