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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM67
All Species:
16.67
Human Site:
S286
Identified Species:
52.38
UniProt:
Q5HYA8
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYA8
NP_001135773.1
995
111731
S286
A
G
L
S
T
V
H
S
I
S
F
W
R
Q
N
Chimpanzee
Pan troglodytes
XP_528307
995
111684
S286
A
G
L
S
T
V
H
S
I
S
F
W
R
Q
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544178
991
111155
S282
A
G
L
R
T
V
H
S
V
S
F
W
R
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BR76
992
111792
S286
A
G
L
I
S
V
H
S
V
P
F
W
R
Q
N
Rat
Rattus norvegicus
P0C152
992
111721
S286
A
G
L
T
G
V
H
S
V
P
F
W
R
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510521
1127
124136
L334
S
R
L
G
I
V
H
L
V
A
T
W
R
K
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700974
982
109506
D274
A
A
Q
G
S
S
Q
D
I
S
Y
W
R
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097846
967
111107
A275
S
D
V
V
M
K
Y
A
H
S
G
E
Q
V
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
89
N.A.
85.1
84.1
N.A.
49.1
N.A.
N.A.
58.6
N.A.
24.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
N.A.
94.2
N.A.
92
91.2
N.A.
61.5
N.A.
N.A.
74.8
N.A.
45
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
73.3
73.3
N.A.
40
N.A.
N.A.
40
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
66.6
N.A.
N.A.
53.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
13
0
0
0
0
0
13
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% F
% Gly:
0
63
0
25
13
0
0
0
0
0
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
75
0
13
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
13
0
0
0
38
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% K
% Leu:
0
0
75
0
0
0
0
13
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
88
% N
% Pro:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% P
% Gln:
0
0
13
0
0
0
13
0
0
0
0
0
13
63
0
% Q
% Arg:
0
13
0
13
0
0
0
0
0
0
0
0
88
0
13
% R
% Ser:
25
0
0
25
25
13
0
63
0
63
0
0
0
0
0
% S
% Thr:
0
0
0
13
38
0
0
0
0
0
13
0
0
13
0
% T
% Val:
0
0
13
13
0
75
0
0
50
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
88
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _