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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX3
All Species:
23.03
Human Site:
S284
Identified Species:
38.97
UniProt:
Q5HYI7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYI7
NP_001010891.3
312
35093
S284
M
D
D
N
L
R
Q
S
P
Q
L
P
P
R
K
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
S284
M
D
D
N
L
R
Q
S
P
Q
L
P
P
R
K
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
S282
M
D
D
N
L
R
Q
S
P
Q
L
P
P
R
K
Dog
Lupus familis
XP_546048
425
47716
S397
M
D
D
N
L
R
Q
S
P
Q
L
P
P
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
Y285
G
L
A
A
M
V
G
Y
A
L
L
S
G
I
V
Rat
Rattus norvegicus
XP_001066436
311
34711
S283
M
D
G
N
L
R
Q
S
P
Q
L
L
P
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
S271
M
D
D
N
L
R
H
S
P
Q
P
P
H
R
K
Chicken
Gallus gallus
NP_001072951
247
27799
E220
F
P
R
V
Q
L
Q
E
H
L
K
Q
L
T
N
Frog
Xenopus laevis
Q3KPT9
309
34626
P282
D
D
N
L
R
R
S
P
Q
N
R
P
Q
K
L
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
D284
N
L
I
E
K
M
D
D
N
L
R
S
S
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB6
327
37234
A293
G
A
V
L
A
M
G
A
F
A
A
W
R
G
I
Honey Bee
Apis mellifera
XP_624291
292
33701
K265
S
Q
N
E
F
P
N
K
R
R
N
Q
L
L
A
Nematode Worm
Caenorhab. elegans
O45503
312
35301
T285
M
R
D
A
I
L
F
T
L
G
A
L
T
L
S
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
V283
L
F
A
A
T
A
M
V
G
Y
A
L
F
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
64.9
N.A.
42.9
90
N.A.
75.6
64.7
69.2
58.1
N.A.
24.7
35.2
31.4
36.6
Protein Similarity:
100
100
88.7
68.9
N.A.
64.3
94.2
N.A.
81.7
72.7
79.8
73.1
N.A.
41.9
51.5
50.3
54.5
P-Site Identity:
100
100
100
100
N.A.
6.6
86.6
N.A.
80
6.6
20
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
86.6
N.A.
80
6.6
33.3
6.6
N.A.
6.6
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
22
8
8
0
8
8
8
22
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
50
43
0
0
0
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
15
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
8
0
8
0
8
0
0
0
8
0
0
% F
% Gly:
15
0
8
0
0
0
15
0
8
8
0
0
8
8
8
% G
% His:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
8
0
0
8
43
% K
% Leu:
8
15
0
15
43
15
0
0
8
22
43
22
15
15
8
% L
% Met:
50
0
0
0
8
15
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
15
43
0
0
8
0
8
8
8
0
0
0
8
% N
% Pro:
0
8
0
0
0
8
0
8
43
0
8
43
36
8
0
% P
% Gln:
0
8
0
0
8
0
43
0
8
43
0
15
8
0
8
% Q
% Arg:
0
8
8
0
8
50
0
0
8
8
15
0
8
43
0
% R
% Ser:
8
0
0
0
0
0
8
43
0
0
0
15
8
8
8
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
8
8
0
% T
% Val:
0
0
8
8
0
8
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _