KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX3
All Species:
21.01
Human Site:
S311
Identified Species:
35.56
UniProt:
Q5HYI7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYI7
NP_001010891.3
312
35093
S311
N
N
S
F
Q
R
L
S
P
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
S311
N
N
S
F
Q
R
L
S
P
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
S309
N
N
S
F
Q
R
L
S
P
_
_
_
_
_
_
Dog
Lupus familis
XP_546048
425
47716
S424
S
N
S
L
Q
R
L
S
P
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
E312
T
R
A
L
G
L
A
E
E
D
E
E
D
_
_
Rat
Rattus norvegicus
XP_001066436
311
34711
S310
S
N
S
S
Q
L
L
S
P
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
S298
D
D
P
S
P
R
P
S
P
_
_
_
_
_
_
Chicken
Gallus gallus
NP_001072951
247
27799
Frog
Xenopus laevis
Q3KPT9
309
34626
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
T311
P
A
S
D
R
N
S
T
P
A
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB6
327
37234
D320
D
G
I
D
Y
E
D
D
E
M
E
E
G
L
D
Honey Bee
Apis mellifera
XP_624291
292
33701
Nematode Worm
Caenorhab. elegans
O45503
312
35301
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
D310
D
D
H
G
M
M
D
D
E
G
D
D
Y
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
64.9
N.A.
42.9
90
N.A.
75.6
64.7
69.2
58.1
N.A.
24.7
35.2
31.4
36.6
Protein Similarity:
100
100
88.7
68.9
N.A.
64.3
94.2
N.A.
81.7
72.7
79.8
73.1
N.A.
41.9
51.5
50.3
54.5
P-Site Identity:
100
100
100
77.7
N.A.
0
66.6
N.A.
33.3
0
0
20
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
88.8
N.A.
7.6
77.7
N.A.
55.5
0
0
40
N.A.
13.3
0
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
15
0
15
0
0
15
15
0
8
8
8
8
0
8
% D
% Glu:
0
0
0
0
0
8
0
8
22
0
15
15
0
0
0
% E
% Phe:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
15
0
15
36
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
22
36
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
8
0
8
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
36
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
8
0
0
8
36
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
43
15
0
0
8
43
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
43
50
50
50
58
58
% _