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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX3
All Species:
18.18
Human Site:
T57
Identified Species:
30.77
UniProt:
Q5HYI7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYI7
NP_001010891.3
312
35093
T57
R
G
D
V
P
I
L
T
T
E
D
D
M
V
S
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
T57
R
G
D
V
P
I
L
T
T
E
D
D
M
V
S
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
E57
D
V
P
I
L
T
T
E
D
N
M
V
S
Q
P
Dog
Lupus familis
XP_546048
425
47716
T170
D
G
D
V
P
I
L
T
T
E
D
N
I
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
T58
G
T
L
P
A
L
R
T
S
D
G
K
V
I
T
Rat
Rattus norvegicus
XP_001066436
311
34711
T57
R
G
D
V
P
I
L
T
T
E
D
S
I
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
N44
S
Q
P
A
K
I
L
N
F
L
R
K
Q
K
Y
Chicken
Gallus gallus
NP_001072951
247
27799
Frog
Xenopus laevis
Q3KPT9
309
34626
G57
V
P
F
L
T
S
A
G
E
D
T
H
Q
P
A
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
H57
T
A
S
V
P
Q
I
H
Y
E
G
T
T
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB6
327
37234
Q59
A
G
K
L
P
Y
L
Q
I
G
N
Q
K
F
A
Honey Bee
Apis mellifera
XP_624291
292
33701
S40
G
I
P
L
K
I
N
S
A
G
N
P
F
T
T
Nematode Worm
Caenorhab. elegans
O45503
312
35301
E58
M
V
A
Q
T
E
G
E
A
K
P
V
T
D
F
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
Y57
S
A
H
Y
P
V
F
Y
S
D
G
R
T
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
64.9
N.A.
42.9
90
N.A.
75.6
64.7
69.2
58.1
N.A.
24.7
35.2
31.4
36.6
Protein Similarity:
100
100
88.7
68.9
N.A.
64.3
94.2
N.A.
81.7
72.7
79.8
73.1
N.A.
41.9
51.5
50.3
54.5
P-Site Identity:
100
100
0
80
N.A.
6.6
86.6
N.A.
13.3
0
0
26.6
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
46.6
93.3
N.A.
13.3
0
20
40
N.A.
40
33.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
8
8
0
8
0
15
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
29
0
0
0
0
0
8
22
29
15
0
8
0
% D
% Glu:
0
0
0
0
0
8
0
15
8
36
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
8
0
0
0
8
8
8
% F
% Gly:
15
36
0
0
0
0
8
8
0
15
22
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
8
0
43
8
0
8
0
0
0
15
8
0
% I
% Lys:
0
0
8
0
15
0
0
0
0
8
0
15
8
8
8
% K
% Leu:
0
0
8
22
8
8
43
0
0
8
0
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
15
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
8
15
8
0
0
0
% N
% Pro:
0
8
22
8
50
0
0
0
0
0
8
8
0
8
8
% P
% Gln:
0
8
0
8
0
8
0
8
0
0
0
8
15
8
0
% Q
% Arg:
22
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% R
% Ser:
15
0
8
0
0
8
0
8
15
0
0
8
8
0
29
% S
% Thr:
8
8
0
0
15
8
8
36
29
0
8
8
22
8
22
% T
% Val:
8
15
0
36
0
8
0
0
0
0
0
15
8
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
8
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _