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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX3
All Species:
28.18
Human Site:
Y118
Identified Species:
47.69
UniProt:
Q5HYI7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYI7
NP_001010891.3
312
35093
Y118
F
W
V
E
S
D
N
Y
F
T
V
T
K
P
W
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
Y118
F
W
V
E
S
D
N
Y
F
T
V
T
K
P
W
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
T118
V
E
S
D
N
Y
F
T
V
T
K
P
W
F
A
Dog
Lupus familis
XP_546048
425
47716
Y231
F
W
V
E
S
D
N
Y
F
T
V
T
K
P
W
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
Y119
F
W
I
D
A
K
N
Y
V
E
V
T
R
K
W
Rat
Rattus norvegicus
XP_001066436
311
34711
Y118
F
W
V
E
N
D
N
Y
F
T
V
T
K
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
F105
W
F
A
A
R
I
P
F
P
L
S
L
I
L
P
Chicken
Gallus gallus
NP_001072951
247
27799
I56
P
K
D
V
P
V
L
I
S
E
D
T
V
I
S
Frog
Xenopus laevis
Q3KPT9
309
34626
V118
D
T
E
N
Y
C
N
V
T
R
P
W
Y
A
S
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
Y118
F
W
V
D
A
E
N
Y
A
N
L
T
R
P
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB6
327
37234
F120
L
F
G
E
P
H
N
F
D
T
T
T
R
G
L
Honey Bee
Apis mellifera
XP_624291
292
33701
K101
Y
G
T
M
L
K
E
K
L
F
P
A
L
Q
F
Nematode Worm
Caenorhab. elegans
O45503
312
35301
Y119
F
W
T
D
E
L
N
Y
N
T
V
T
Q
Y
W
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
Y118
W
W
V
D
A
K
N
Y
T
E
F
S
R
P
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
64.9
N.A.
42.9
90
N.A.
75.6
64.7
69.2
58.1
N.A.
24.7
35.2
31.4
36.6
Protein Similarity:
100
100
88.7
68.9
N.A.
64.3
94.2
N.A.
81.7
72.7
79.8
73.1
N.A.
41.9
51.5
50.3
54.5
P-Site Identity:
100
100
6.6
100
N.A.
46.6
93.3
N.A.
0
6.6
6.6
53.3
N.A.
26.6
0
53.3
40
P-Site Similarity:
100
100
20
100
N.A.
73.3
100
N.A.
20
6.6
6.6
86.6
N.A.
46.6
13.3
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
22
0
0
0
8
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
36
0
29
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
8
8
36
8
8
8
0
0
22
0
0
0
0
0
% E
% Phe:
50
15
0
0
0
0
8
15
29
8
8
0
0
8
8
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
8
0
0
0
0
8
8
0
% I
% Lys:
0
8
0
0
0
22
0
8
0
0
8
0
29
8
0
% K
% Leu:
8
0
0
0
8
8
8
0
8
8
8
8
8
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
15
0
72
0
8
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
15
0
8
0
8
0
15
8
0
43
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
0
0
29
0
0
% R
% Ser:
0
0
8
0
22
0
0
0
8
0
8
8
0
0
15
% S
% Thr:
0
8
15
0
0
0
0
8
15
50
8
65
0
0
0
% T
% Val:
8
0
43
8
0
8
0
8
15
0
43
0
8
0
0
% V
% Trp:
15
58
0
0
0
0
0
0
0
0
0
8
8
0
58
% W
% Tyr:
8
0
0
0
8
8
0
58
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _