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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX3
All Species:
22.73
Human Site:
Y170
Identified Species:
38.46
UniProt:
Q5HYI7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYI7
NP_001010891.3
312
35093
Y170
R
E
V
E
A
Q
I
Y
R
D
A
K
E
C
L
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
Y170
R
E
V
E
A
Q
I
Y
R
D
A
K
E
C
L
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
D170
V
E
A
Q
I
Y
R
D
A
K
E
C
L
N
L
Dog
Lupus familis
XP_546048
425
47716
Y283
R
E
V
E
A
Q
I
Y
R
D
A
K
E
C
L
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
Y171
E
E
L
E
K
E
L
Y
Q
E
A
R
E
C
L
Rat
Rattus norvegicus
XP_001066436
311
34711
Y170
Q
D
V
E
A
Q
I
Y
R
D
A
K
E
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
L157
L
N
L
L
S
N
R
L
G
T
S
P
F
F
F
Chicken
Gallus gallus
NP_001072951
247
27799
H108
K
L
L
P
A
L
L
H
T
F
W
V
E
A
E
Frog
Xenopus laevis
Q3KPT9
309
34626
A170
E
A
Q
I
Y
K
D
A
K
E
C
L
N
L
F
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
Y170
T
E
V
E
G
K
I
Y
S
E
A
K
E
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB6
327
37234
L172
D
K
H
E
G
D
Y
L
V
V
N
A
K
K
V
Honey Bee
Apis mellifera
XP_624291
292
33701
Y153
H
T
M
F
V
T
L
Y
P
L
E
D
N
I
T
Nematode Worm
Caenorhab. elegans
O45503
312
35301
S171
F
M
A
L
N
T
L
S
T
K
L
G
D
N
K
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
K170
E
L
S
Q
N
V
M
K
D
A
R
Y
C
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
64.9
N.A.
42.9
90
N.A.
75.6
64.7
69.2
58.1
N.A.
24.7
35.2
31.4
36.6
Protein Similarity:
100
100
88.7
68.9
N.A.
64.3
94.2
N.A.
81.7
72.7
79.8
73.1
N.A.
41.9
51.5
50.3
54.5
P-Site Identity:
100
100
13.3
100
N.A.
46.6
86.6
N.A.
0
13.3
0
66.6
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
20
100
N.A.
86.6
100
N.A.
20
40
20
80
N.A.
26.6
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
36
0
0
8
8
8
43
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
8
43
0
% C
% Asp:
8
8
0
0
0
8
8
8
8
29
0
8
8
0
0
% D
% Glu:
22
43
0
50
0
8
0
0
0
22
15
0
50
0
8
% E
% Phe:
8
0
0
8
0
0
0
0
0
8
0
0
8
8
15
% F
% Gly:
0
0
0
0
15
0
0
0
8
0
0
8
0
0
0
% G
% His:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
36
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
0
0
8
15
0
8
8
15
0
36
8
8
8
% K
% Leu:
8
15
22
15
0
8
29
15
0
8
8
8
8
15
50
% L
% Met:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
15
8
0
0
0
0
8
0
15
15
8
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% P
% Gln:
8
0
8
15
0
29
0
0
8
0
0
0
0
0
0
% Q
% Arg:
22
0
0
0
0
0
15
0
29
0
8
8
0
0
0
% R
% Ser:
0
0
8
0
8
0
0
8
8
0
8
0
0
0
0
% S
% Thr:
8
8
0
0
0
15
0
0
15
8
0
0
0
0
8
% T
% Val:
8
0
36
0
8
8
0
0
8
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
8
50
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _