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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3D19
All Species:
19.7
Human Site:
Y739
Identified Species:
54.17
UniProt:
Q5HYK7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYK7
NP_001009555.3
790
86525
Y739
G
R
K
A
K
A
L
Y
D
F
R
G
E
N
E
Chimpanzee
Pan troglodytes
XP_001152369
787
86103
Y736
G
R
K
A
K
A
L
Y
D
F
R
G
E
N
E
Rhesus Macaque
Macaca mulatta
XP_001082920
787
85765
Y736
G
R
K
A
K
A
L
Y
D
F
R
G
E
N
E
Dog
Lupus familis
XP_539763
786
85616
Y735
G
K
K
A
K
A
L
Y
D
F
H
G
E
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91X43
789
86058
Y738
G
R
K
V
K
A
L
Y
D
F
L
G
E
N
E
Rat
Rattus norvegicus
Q9WVE9
1217
137136
Y1161
V
C
Q
V
I
G
M
Y
D
Y
T
A
Q
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511455
557
60881
D507
E
K
A
R
A
L
Y
D
F
H
G
E
N
D
D
Chicken
Gallus gallus
XP_420444
779
86598
M728
R
K
K
P
K
L
S
M
I
L
M
V
K
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793803
946
99809
A893
A
G
A
T
P
S
T
A
K
A
L
H
D
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
97
84.1
N.A.
78.3
20.2
N.A.
47.8
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
98.9
98.2
89.6
N.A.
86
33.3
N.A.
56.4
53.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.4
P-Site Identity:
100
100
100
86.6
N.A.
86.6
20
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
53.3
N.A.
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
45
12
56
0
12
0
12
0
12
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
67
0
0
0
12
12
34
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
0
12
56
0
56
% E
% Phe:
0
0
0
0
0
0
0
0
12
56
0
0
0
12
0
% F
% Gly:
56
12
0
0
0
12
0
0
0
0
12
56
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
12
12
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
34
67
0
67
0
0
0
12
0
0
0
12
0
12
% K
% Leu:
0
0
0
0
0
23
56
0
0
12
23
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
12
0
0
12
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
67
0
% N
% Pro:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
12
45
0
12
0
0
0
0
0
0
34
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
12
0
0
0
12
0
0
0
0
% T
% Val:
12
0
0
23
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
67
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _