KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM196
All Species:
5.45
Human Site:
T162
Identified Species:
20
UniProt:
Q5HYL7
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYL7
NP_689987.3
178
19025
T162
E
M
A
E
K
E
I
T
D
N
M
S
N
G
G
Chimpanzee
Pan troglodytes
XP_001151953
111
12357
V100
T
D
L
P
S
C
P
V
V
P
P
T
P
E
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5EB63
176
18828
T156
E
M
A
E
K
E
V
T
D
N
M
S
N
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513164
104
11527
N93
E
M
T
D
N
M
S
N
G
A
P
P
L
I
Y
Chicken
Gallus gallus
XP_001234722
183
19615
R160
E
M
A
E
K
R
L
R
G
I
E
I
T
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338909
175
18986
L156
E
M
A
E
K
E
V
L
D
N
T
S
N
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18779
329
36875
T303
S
I
L
Y
T
Y
V
T
F
R
S
K
S
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.4
N.A.
N.A.
N.A.
N.A.
94.3
N.A.
54.4
83
N.A.
67.9
N.A.
N.A.
N.A.
21.5
N.A.
Protein Similarity:
100
51.1
N.A.
N.A.
N.A.
N.A.
95.5
N.A.
56.7
86.8
N.A.
82
N.A.
N.A.
N.A.
31.9
N.A.
P-Site Identity:
100
0
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
13.3
33.3
N.A.
73.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
20
40
N.A.
80
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
58
0
0
0
0
0
0
15
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
15
0
0
0
0
43
0
0
0
0
15
0
% D
% Glu:
72
0
0
58
0
43
0
0
0
0
15
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
29
0
0
0
0
43
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
15
0
0
15
0
15
0
15
15
% I
% Lys:
0
0
0
0
58
0
0
0
0
0
0
15
0
0
0
% K
% Leu:
0
0
29
0
0
0
15
15
0
0
0
0
15
0
29
% L
% Met:
0
72
0
0
0
15
0
0
0
0
29
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
15
0
43
0
0
43
0
0
% N
% Pro:
0
0
0
15
0
0
15
0
0
15
29
15
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
15
0
15
0
0
0
0
0
% R
% Ser:
15
0
0
0
15
0
15
0
0
0
15
43
15
0
0
% S
% Thr:
15
0
15
0
15
0
0
43
0
0
15
15
15
15
15
% T
% Val:
0
0
0
0
0
0
43
15
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
15
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _