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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRB2 All Species: 20
Human Site: S1259 Identified Species: 44
UniProt: Q5IJ48 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5IJ48 NP_775960.4 1285 134265 S1259 R Q S E G T Y S P S Q Q E V A
Chimpanzee Pan troglodytes XP_528426 1285 134111 S1259 R Q S E G T Y S P S Q Q E V A
Rhesus Macaque Macaca mulatta XP_001083811 1288 134703 S1262 R Q S E G T Y S P S Q Q E V A
Dog Lupus familis XP_548462 1146 119389 A1122 R A D P C R P A P C A R G R C
Cat Felis silvestris
Mouse Mus musculus Q80YA8 1282 134742 S1256 R Q S E G T Y S P S Q Q E V A
Rat Rattus norvegicus Q07008 2531 270981 L2362 Q G L P N T R L A T Q P H L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415389 1019 111157 Q997 G T Y S P S Q Q E V A G A R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio P46530 2437 262289 H2410 Q W S S S S P H S N L S D W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10040 2146 233554 S2120 R A T R G T Y S P S A Q E Y C
Honey Bee Apis mellifera XP_001121416 2144 234931 S2118 R A T R G T Y S P S A Q E F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 K1042 S T C Q D I K K S N M V G Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.7 70.7 N.A. 78.4 21.3 N.A. N.A. 32.4 N.A. 20.3 N.A. 23.8 23.9 N.A. 22.8
Protein Similarity: 100 98.9 96 75.3 N.A. 83.5 29.7 N.A. N.A. 44 N.A. 30.3 N.A. 34.7 35.6 N.A. 34.7
P-Site Identity: 100 100 100 13.3 N.A. 100 13.3 N.A. N.A. 0 N.A. 6.6 N.A. 60 60 N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 100 33.3 N.A. N.A. 6.6 N.A. 40 N.A. 66.6 73.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 0 0 0 10 10 0 37 0 10 0 37 % A
% Cys: 0 0 10 0 10 0 0 0 0 10 0 0 0 0 19 % C
% Asp: 0 0 10 0 10 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 37 0 0 0 0 10 0 0 0 55 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 10 0 0 55 0 0 0 0 0 0 10 19 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 10 0 0 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 19 0 0 0 0 0 % N
% Pro: 0 0 0 19 10 0 19 0 64 0 0 10 0 0 0 % P
% Gln: 19 37 0 10 0 0 10 10 0 0 46 55 0 10 0 % Q
% Arg: 64 0 0 19 0 10 10 0 0 0 0 10 0 19 0 % R
% Ser: 10 0 46 19 10 19 0 55 19 55 0 10 0 0 19 % S
% Thr: 0 19 19 0 0 64 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 10 0 37 10 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 10 0 0 0 55 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _