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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRB2 All Species: 18.79
Human Site: T480 Identified Species: 41.33
UniProt: Q5IJ48 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5IJ48 NP_775960.4 1285 134265 T480 T L A T R N D T K E S L E L A
Chimpanzee Pan troglodytes XP_528426 1285 134111 T480 T L A T R N D T K E S L E L A
Rhesus Macaque Macaca mulatta XP_001083811 1288 134703 T483 T L A T R N D T R E S L E L A
Dog Lupus familis XP_548462 1146 119389 S498 A L A T R T D S Q D S L E L A
Cat Felis silvestris
Mouse Mus musculus Q80YA8 1282 134742 T484 T L A T L K D T R D S L E L V
Rat Rattus norvegicus Q07008 2531 270981 C650 D D C A S N P C D S G T C L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415389 1019 111157 F407 L S T D T V T F P E N L V D G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio P46530 2437 262289 S989 T P D C T E S S C F N G G T C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10040 2146 233554 T1062 G V L A F G T T G E K N E P V
Honey Bee Apis mellifera XP_001121416 2144 234931 G1062 G L L A I G K G S T F Y I L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 C451 D E C A S R P C Q N G A V C V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.7 70.7 N.A. 78.4 21.3 N.A. N.A. 32.4 N.A. 20.3 N.A. 23.8 23.9 N.A. 22.8
Protein Similarity: 100 98.9 96 75.3 N.A. 83.5 29.7 N.A. N.A. 44 N.A. 30.3 N.A. 34.7 35.6 N.A. 34.7
P-Site Identity: 100 100 93.3 66.6 N.A. 66.6 13.3 N.A. N.A. 13.3 N.A. 6.6 N.A. 20 13.3 N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 80 13.3 N.A. N.A. 20 N.A. 20 N.A. 26.6 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 46 37 0 0 0 0 0 0 0 10 0 0 37 % A
% Cys: 0 0 19 10 0 0 0 19 10 0 0 0 10 10 10 % C
% Asp: 19 10 10 10 0 0 46 0 10 19 0 0 0 10 10 % D
% Glu: 0 10 0 0 0 10 0 0 0 46 0 0 55 0 10 % E
% Phe: 0 0 0 0 10 0 0 10 0 10 10 0 0 0 0 % F
% Gly: 19 0 0 0 0 19 0 10 10 0 19 10 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 10 10 0 19 0 10 0 0 0 0 % K
% Leu: 10 55 19 0 10 0 0 0 0 0 0 55 0 64 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 37 0 0 0 10 19 10 0 0 0 % N
% Pro: 0 10 0 0 0 0 19 0 10 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 37 10 0 0 19 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 19 0 10 19 10 10 46 0 0 0 0 % S
% Thr: 46 0 10 46 19 10 19 46 0 10 0 10 0 10 0 % T
% Val: 0 10 0 0 0 10 0 0 0 0 0 0 19 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _