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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM85 All Species: 32.12
Human Site: S126 Identified Species: 58.89
UniProt: Q5J8M3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5J8M3 NP_057538.1 183 20087 S126 T F K M L E S S S Q K F L Q G
Chimpanzee Pan troglodytes XP_510280 184 19959 S127 T F K M L E S S S Q K F L Q G
Rhesus Macaque Macaca mulatta XP_001087127 149 16712 T93 I M Y M A G N T I S I F P T M
Dog Lupus familis XP_535416 183 20068 S126 T F K M L E S S S Q K F L Q G
Cat Felis silvestris
Mouse Mus musculus Q9CZX9 183 20098 S126 T F K M L E S S S Q K F L Q G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515688 180 19731 S123 T F K M L E S S S Q K L L Q G
Chicken Gallus gallus
Frog Xenopus laevis Q6GR43 180 19964 S123 T F K L L E S S G Q R F L Q G
Zebra Danio Brachydanio rerio Q6P011 189 20674 S132 T F K L L E S S S Q Q W L Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649424 166 18329 G108 V T S K M A E G A Q G T G Q R
Honey Bee Apis mellifera XP_395810 224 25140 G117 Q T F K V I E G T H A F G Q K
Nematode Worm Caenorhab. elegans NP_500802 174 19262 T116 K P L E S P A T G S M F I H K
Sea Urchin Strong. purpuratus XP_785728 209 23426 S152 T Y K M L E G S P Q A L I Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53073 190 21441 N130 A F K P V L G N K A T Q S Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 69.4 97.8 N.A. 99.4 N.A. N.A. 93.4 N.A. 83 75.1 N.A. 50.2 41.5 36.6 49.7
Protein Similarity: 100 94.5 76.5 97.8 N.A. 99.4 N.A. N.A. 95 N.A. 87.9 85.7 N.A. 66.1 54 54 64.5
P-Site Identity: 100 100 13.3 100 N.A. 100 N.A. N.A. 93.3 N.A. 80 80 N.A. 13.3 13.3 6.6 53.3
P-Site Similarity: 100 100 26.6 100 N.A. 100 N.A. N.A. 93.3 N.A. 93.3 100 N.A. 26.6 26.6 26.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 8 8 0 8 8 16 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 62 16 0 0 0 0 0 0 0 0 % E
% Phe: 0 62 8 0 0 0 0 0 0 0 0 62 0 0 0 % F
% Gly: 0 0 0 0 0 8 16 16 16 0 8 0 16 0 54 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 8 0 0 0 0 8 0 0 8 0 8 0 16 0 0 % I
% Lys: 8 0 70 16 0 0 0 0 8 0 39 0 0 0 24 % K
% Leu: 0 0 8 16 62 8 0 0 0 0 0 16 54 0 0 % L
% Met: 0 8 0 54 8 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 0 8 0 0 8 0 0 0 8 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 70 8 8 0 85 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % R
% Ser: 0 0 8 0 8 0 54 62 47 16 0 0 8 0 0 % S
% Thr: 62 16 0 0 0 0 0 16 8 0 8 8 0 8 0 % T
% Val: 8 0 0 0 16 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _