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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM85
All Species:
36
Human Site:
S177
Identified Species:
65.99
UniProt:
Q5J8M3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5J8M3
NP_057538.1
183
20087
S177
P
P
E
R
M
E
F
S
G
G
G
L
L
L
_
Chimpanzee
Pan troglodytes
XP_510280
184
19959
S178
P
P
E
R
M
E
F
S
G
G
G
L
L
L
_
Rhesus Macaque
Macaca mulatta
XP_001087127
149
16712
Dog
Lupus familis
XP_535416
183
20068
S177
P
P
E
R
M
E
F
S
G
G
G
L
L
L
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX9
183
20098
S177
P
P
E
R
M
E
F
S
G
G
G
L
L
L
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515688
180
19731
S174
P
P
E
R
M
E
L
S
G
G
G
L
L
L
_
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR43
180
19964
T174
P
P
E
R
M
E
Y
T
G
G
G
F
L
L
_
Zebra Danio
Brachydanio rerio
Q6P011
189
20674
M183
P
P
Q
R
L
E
I
M
G
G
G
M
V
M
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649424
166
18329
Y159
P
Q
T
R
L
E
Y
Y
G
G
G
I
S
F
V
Honey Bee
Apis mellifera
XP_395810
224
25140
S168
P
Q
A
R
L
E
Y
S
G
G
G
F
I
Y
F
Nematode Worm
Caenorhab. elegans
NP_500802
174
19262
S167
Q
P
G
R
A
Q
Y
S
I
I
D
E
V
F
I
Sea Urchin
Strong. purpuratus
XP_785728
209
23426
S203
P
Q
Q
R
V
E
Y
S
G
G
G
M
V
L
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53073
190
21441
Y181
P
W
E
R
I
A
H
Y
N
N
G
L
Q
W
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
69.4
97.8
N.A.
99.4
N.A.
N.A.
93.4
N.A.
83
75.1
N.A.
50.2
41.5
36.6
49.7
Protein Similarity:
100
94.5
76.5
97.8
N.A.
99.4
N.A.
N.A.
95
N.A.
87.9
85.7
N.A.
66.1
54
54
64.5
P-Site Identity:
100
100
0
100
N.A.
100
N.A.
N.A.
92.8
N.A.
78.5
50
N.A.
40
46.6
20
57.1
P-Site Similarity:
100
100
0
100
N.A.
100
N.A.
N.A.
92.8
N.A.
92.8
85.7
N.A.
60
66.6
46.6
92.8
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
54
0
0
77
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
31
0
0
0
0
16
0
16
16
% F
% Gly:
0
0
8
0
0
0
0
0
77
77
85
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
8
8
0
8
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
24
0
8
0
0
0
0
47
47
54
0
% L
% Met:
0
0
0
0
47
0
0
8
0
0
0
16
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
85
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
24
16
0
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
62
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
24
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
39
16
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% _