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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM85 All Species: 15.15
Human Site: S28 Identified Species: 27.78
UniProt: Q5J8M3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5J8M3 NP_057538.1 183 20087 S28 L S G P G G G S R G R S D R G
Chimpanzee Pan troglodytes XP_510280 184 19959 S29 L S A L G G G S R G R S D R G
Rhesus Macaque Macaca mulatta XP_001087127 149 16712 R11 Q G G L V A N R G R R F K W A
Dog Lupus familis XP_535416 183 20068 S28 L S G P G G G S R S R S D R G
Cat Felis silvestris
Mouse Mus musculus Q9CZX9 183 20098 S28 L S G P G G G S R G R S D R G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515688 180 19731 G25 V S G P S G G G R G R S D R G
Chicken Gallus gallus
Frog Xenopus laevis Q6GR43 180 19964 G25 A I E F G S G G S R G R G E R
Zebra Danio Brachydanio rerio Q6P011 189 20674 S34 V E L S L G N S R S R S D R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649424 166 18329 D23 F N G S K N A D I P S P L G Y
Honey Bee Apis mellifera XP_395810 224 25140 E24 F A H K S K Q E K N A D I A S
Nematode Worm Caenorhab. elegans NP_500802 174 19262 P26 T A D S N F N P P G F Y S T A
Sea Urchin Strong. purpuratus XP_785728 209 23426 P37 R A Q A A F T P P R R T D S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53073 190 21441 N39 S P P G F E G N S S K G N V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 69.4 97.8 N.A. 99.4 N.A. N.A. 93.4 N.A. 83 75.1 N.A. 50.2 41.5 36.6 49.7
Protein Similarity: 100 94.5 76.5 97.8 N.A. 99.4 N.A. N.A. 95 N.A. 87.9 85.7 N.A. 66.1 54 54 64.5
P-Site Identity: 100 86.6 13.3 93.3 N.A. 100 N.A. N.A. 80 N.A. 13.3 46.6 N.A. 6.6 0 6.6 13.3
P-Site Similarity: 100 86.6 13.3 93.3 N.A. 100 N.A. N.A. 86.6 N.A. 13.3 53.3 N.A. 13.3 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 24 8 8 8 8 8 0 0 0 8 0 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 8 0 0 0 8 54 0 0 % D
% Glu: 0 8 8 0 0 8 0 8 0 0 0 0 0 8 8 % E
% Phe: 16 0 0 8 8 16 0 0 0 0 8 8 0 0 0 % F
% Gly: 0 8 47 8 39 47 54 16 8 39 8 8 8 8 39 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 8 0 0 0 8 0 0 % I
% Lys: 0 0 0 8 8 8 0 0 8 0 8 0 8 0 0 % K
% Leu: 31 0 8 16 8 0 0 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 8 24 8 0 8 0 0 8 0 0 % N
% Pro: 0 8 8 31 0 0 0 16 16 8 0 8 0 0 0 % P
% Gln: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 8 % Q
% Arg: 8 0 0 0 0 0 0 8 47 24 62 8 0 47 8 % R
% Ser: 8 39 0 24 16 8 0 39 16 24 8 47 8 8 8 % S
% Thr: 8 0 0 0 0 0 8 0 0 0 0 8 0 8 8 % T
% Val: 16 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _