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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM85 All Species: 21.21
Human Site: S41 Identified Species: 38.89
UniProt: Q5J8M3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5J8M3 NP_057538.1 183 20087 S41 R G S G Q G D S L Y P V G Y L
Chimpanzee Pan troglodytes XP_510280 184 19959 S42 R G S G Q G D S L Y P V G Y L
Rhesus Macaque Macaca mulatta XP_001087127 149 16712 P24 W A I E L S G P G G G S R G R
Dog Lupus familis XP_535416 183 20068 S41 R G G G Q G D S L Y P V G Y L
Cat Felis silvestris
Mouse Mus musculus Q9CZX9 183 20098 S41 R G S G Q G D S L Y P V G Y L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515688 180 19731 S38 R G S G Q G D S L Y P V G Y L
Chicken Gallus gallus
Frog Xenopus laevis Q6GR43 180 19964 S38 E R G G L Q D S M Y P V G Y S
Zebra Danio Brachydanio rerio Q6P011 189 20674 V47 R Q G K D G D V M Y P V G Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649424 166 18329 V36 G Y N P S A L V N Q S E V V R
Honey Bee Apis mellifera XP_395810 224 25140 P37 A S P P G Y T P A V A L F H A
Nematode Worm Caenorhab. elegans NP_500802 174 19262 S39 T A A T V Q H S A E A D R S A
Sea Urchin Strong. purpuratus XP_785728 209 23426 A50 S E F G R Y T A V H V M P R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53073 190 21441 A52 V T R K Q Q D A T S Q T T S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 69.4 97.8 N.A. 99.4 N.A. N.A. 93.4 N.A. 83 75.1 N.A. 50.2 41.5 36.6 49.7
Protein Similarity: 100 94.5 76.5 97.8 N.A. 99.4 N.A. N.A. 95 N.A. 87.9 85.7 N.A. 66.1 54 54 64.5
P-Site Identity: 100 100 0 93.3 N.A. 100 N.A. N.A. 100 N.A. 53.3 53.3 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 0 93.3 N.A. 100 N.A. N.A. 100 N.A. 60 60 N.A. 6.6 13.3 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 0 0 8 0 16 16 0 16 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 62 0 0 0 0 8 0 0 0 % D
% Glu: 8 8 0 8 0 0 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 39 24 54 8 47 8 0 8 8 8 0 54 8 0 % G
% His: 0 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 16 0 8 0 39 0 0 8 0 0 47 % L
% Met: 0 0 0 0 0 0 0 0 16 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 8 16 0 0 0 16 0 0 54 0 8 0 0 % P
% Gln: 0 8 0 0 47 24 0 0 0 8 8 0 0 0 0 % Q
% Arg: 47 8 8 0 8 0 0 0 0 0 0 0 16 8 16 % R
% Ser: 8 8 31 0 8 8 0 54 0 8 8 8 0 16 24 % S
% Thr: 8 8 0 8 0 0 16 0 8 0 0 8 8 0 0 % T
% Val: 8 0 0 0 8 0 0 16 8 8 8 54 8 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 16 0 0 0 54 0 0 0 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _