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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM85
All Species:
25.76
Human Site:
S56
Identified Species:
47.22
UniProt:
Q5J8M3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5J8M3
NP_057538.1
183
20087
S56
D
K
Q
V
P
D
T
S
V
Q
E
T
D
R
I
Chimpanzee
Pan troglodytes
XP_510280
184
19959
S57
D
K
Q
V
P
D
T
S
V
Q
E
T
D
R
I
Rhesus Macaque
Macaca mulatta
XP_001087127
149
16712
G39
S
D
R
G
S
G
Q
G
D
S
L
Y
P
V
G
Dog
Lupus familis
XP_535416
183
20068
S56
D
K
Q
V
P
D
T
S
V
Q
E
A
D
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX9
183
20098
S56
D
K
Q
V
P
D
T
S
V
Q
E
T
D
R
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515688
180
19731
S53
D
K
Q
V
P
D
T
S
V
Q
E
T
D
R
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR43
180
19964
S53
D
K
Q
V
P
D
T
S
V
Q
E
S
D
H
I
Zebra Danio
Brachydanio rerio
Q6P011
189
20674
S62
D
K
P
V
P
D
T
S
V
Q
E
A
D
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649424
166
18329
K51
D
Q
R
L
V
I
K
K
S
W
D
L
A
L
G
Honey Bee
Apis mellifera
XP_395810
224
25140
D52
A
D
S
I
R
E
S
D
S
N
H
L
I
I
K
Nematode Worm
Caenorhab. elegans
NP_500802
174
19262
R54
D
Q
H
E
H
L
A
R
K
R
V
W
D
T
A
Sea Urchin
Strong. purpuratus
XP_785728
209
23426
A65
E
R
Q
L
Q
A
I
A
D
H
P
S
P
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53073
190
21441
V67
A
Q
K
N
Q
I
T
V
L
Q
V
Q
K
A
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
69.4
97.8
N.A.
99.4
N.A.
N.A.
93.4
N.A.
83
75.1
N.A.
50.2
41.5
36.6
49.7
Protein Similarity:
100
94.5
76.5
97.8
N.A.
99.4
N.A.
N.A.
95
N.A.
87.9
85.7
N.A.
66.1
54
54
64.5
P-Site Identity:
100
100
0
93.3
N.A.
100
N.A.
N.A.
100
N.A.
86.6
80
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
100
N.A.
N.A.
100
N.A.
93.3
80
N.A.
33.3
20
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
8
8
8
0
0
0
16
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
16
0
0
0
54
0
8
16
0
8
0
62
0
0
% D
% Glu:
8
0
0
8
0
8
0
0
0
0
54
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
24
% G
% His:
0
0
8
0
8
0
0
0
0
8
8
0
0
8
0
% H
% Ile:
0
0
0
8
0
16
8
0
0
0
0
0
8
16
47
% I
% Lys:
0
54
8
0
0
0
8
8
8
0
0
0
8
0
8
% K
% Leu:
0
0
0
16
0
8
0
0
8
0
8
16
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
8
0
54
0
0
0
0
0
8
0
16
0
0
% P
% Gln:
0
24
54
0
16
0
8
0
0
62
0
8
0
0
0
% Q
% Arg:
0
8
16
0
8
0
0
8
0
8
0
0
0
47
0
% R
% Ser:
8
0
8
0
8
0
8
54
16
8
0
16
0
0
0
% S
% Thr:
0
0
0
0
0
0
62
0
0
0
0
31
0
8
0
% T
% Val:
0
0
0
54
8
0
0
8
54
0
16
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _