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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM85 All Species: 28.48
Human Site: Y47 Identified Species: 52.22
UniProt: Q5J8M3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5J8M3 NP_057538.1 183 20087 Y47 D S L Y P V G Y L D K Q V P D
Chimpanzee Pan troglodytes XP_510280 184 19959 Y48 D S L Y P V G Y L D K Q V P D
Rhesus Macaque Macaca mulatta XP_001087127 149 16712 G30 G P G G G S R G R S D R G S G
Dog Lupus familis XP_535416 183 20068 Y47 D S L Y P V G Y L D K Q V P D
Cat Felis silvestris
Mouse Mus musculus Q9CZX9 183 20098 Y47 D S L Y P V G Y L D K Q V P D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515688 180 19731 Y44 D S L Y P V G Y L D K Q V P D
Chicken Gallus gallus
Frog Xenopus laevis Q6GR43 180 19964 Y44 D S M Y P V G Y S D K Q V P D
Zebra Danio Brachydanio rerio Q6P011 189 20674 Y53 D V M Y P V G Y S D K P V P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649424 166 18329 V42 L V N Q S E V V R D Q R L V I
Honey Bee Apis mellifera XP_395810 224 25140 H43 T P A V A L F H A A D S I R E
Nematode Worm Caenorhab. elegans NP_500802 174 19262 S45 H S A E A D R S A D Q H E H L
Sea Urchin Strong. purpuratus XP_785728 209 23426 R56 T A V H V M P R S E R Q L Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53073 190 21441 S58 D A T S Q T T S L A Q K N Q I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 69.4 97.8 N.A. 99.4 N.A. N.A. 93.4 N.A. 83 75.1 N.A. 50.2 41.5 36.6 49.7
Protein Similarity: 100 94.5 76.5 97.8 N.A. 99.4 N.A. N.A. 95 N.A. 87.9 85.7 N.A. 66.1 54 54 64.5
P-Site Identity: 100 100 0 100 N.A. 100 N.A. N.A. 100 N.A. 86.6 73.3 N.A. 6.6 0 13.3 6.6
P-Site Similarity: 100 100 6.6 100 N.A. 100 N.A. N.A. 100 N.A. 93.3 80 N.A. 26.6 26.6 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 0 16 0 0 0 16 16 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 62 0 0 0 0 8 0 0 0 70 16 0 0 0 54 % D
% Glu: 0 0 0 8 0 8 0 0 0 8 0 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 8 8 0 54 8 0 0 0 0 8 0 8 % G
% His: 8 0 0 8 0 0 0 8 0 0 0 8 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 16 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 54 8 0 0 0 % K
% Leu: 8 0 39 0 0 8 0 0 47 0 0 0 16 0 8 % L
% Met: 0 0 16 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 16 0 0 54 0 8 0 0 0 0 8 0 54 0 % P
% Gln: 0 0 0 8 8 0 0 0 0 0 24 54 0 16 0 % Q
% Arg: 0 0 0 0 0 0 16 8 16 0 8 16 0 8 0 % R
% Ser: 0 54 0 8 8 8 0 16 24 8 0 8 0 8 0 % S
% Thr: 16 0 8 0 0 8 8 0 0 0 0 0 0 0 0 % T
% Val: 0 16 8 8 8 54 8 8 0 0 0 0 54 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 54 0 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _