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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL10
All Species:
2.42
Human Site:
S269
Identified Species:
7.62
UniProt:
Q5JPI9
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JPI9
NP_997719.2
291
31830
S269
A
G
L
E
L
L
G
S
S
D
S
P
T
W
P
Chimpanzee
Pan troglodytes
XP_508097
236
25886
T215
E
L
L
E
E
L
P
T
P
K
F
S
F
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D853
244
26846
R223
P
K
F
S
F
G
G
R
S
G
N
T
V
A
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421814
219
24268
T197
E
V
V
E
E
L
P
T
P
K
F
C
F
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5D013
233
26015
P212
L
V
R
E
L
P
T
P
N
F
Q
F
G
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608733
219
24719
P197
K
Y
Y
T
I
P
T
P
T
F
K
F
G
G
K
Honey Bee
Apis mellifera
XP_624562
221
25338
A200
D
I
L
H
V
L
P
A
D
T
F
I
F
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40516
257
28671
P236
M
W
K
T
I
K
Y
P
V
F
Q
F
G
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
N.A.
N.A.
N.A.
64.9
N.A.
N.A.
N.A.
53.9
N.A.
45.3
N.A.
34
32.6
N.A.
N.A.
Protein Similarity:
100
76.9
N.A.
N.A.
N.A.
72.1
N.A.
N.A.
N.A.
62.5
N.A.
60.1
N.A.
51.5
50.5
N.A.
N.A.
P-Site Identity:
100
20
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
13.3
N.A.
13.3
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
26.6
N.A.
20
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
13
0
0
0
0
0
25
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% D
% Glu:
25
0
0
50
25
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
0
13
0
0
0
0
38
38
38
38
0
0
% F
% Gly:
0
13
0
0
0
13
25
0
0
13
0
0
38
63
38
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
25
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
13
13
13
0
0
13
0
0
0
25
13
0
0
0
13
% K
% Leu:
13
13
38
0
25
50
0
0
0
0
0
0
0
0
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% N
% Pro:
13
0
0
0
0
25
38
38
25
0
0
13
0
0
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
0
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
0
0
0
13
25
0
13
13
0
0
0
% S
% Thr:
0
0
0
25
0
0
25
25
13
13
0
13
13
0
0
% T
% Val:
0
25
13
0
13
0
0
0
13
0
0
0
13
0
25
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
13
13
0
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _