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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL10
All Species:
0.61
Human Site:
Y173
Identified Species:
1.9
UniProt:
Q5JPI9
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JPI9
NP_997719.2
291
31830
Y173
A
I
E
K
R
K
Q
Y
V
K
S
L
S
R
V
Chimpanzee
Pan troglodytes
XP_508097
236
25886
G119
P
S
A
I
Q
L
S
G
S
I
I
E
K
E
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D853
244
26846
L127
S
I
L
E
K
E
G
L
S
N
I
N
L
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421814
219
24268
E101
P
S
A
I
Q
L
S
E
K
V
R
E
K
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5D013
233
26015
N116
A
A
L
E
L
T
T
N
I
L
V
E
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608733
219
24719
N101
K
A
V
E
L
A
Q
N
I
A
E
D
N
K
L
Honey Bee
Apis mellifera
XP_624562
221
25338
V104
A
V
D
L
A
R
E
V
S
K
E
N
N
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40516
257
28671
T140
A
S
N
I
A
E
A
T
G
V
D
N
F
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
N.A.
N.A.
N.A.
64.9
N.A.
N.A.
N.A.
53.9
N.A.
45.3
N.A.
34
32.6
N.A.
N.A.
Protein Similarity:
100
76.9
N.A.
N.A.
N.A.
72.1
N.A.
N.A.
N.A.
62.5
N.A.
60.1
N.A.
51.5
50.5
N.A.
N.A.
P-Site Identity:
100
0
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
6.6
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
6.6
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
6.6
N.A.
26.6
N.A.
40
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
25
25
0
25
13
13
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
13
13
0
0
0
% D
% Glu:
0
0
13
38
0
25
13
13
0
0
25
38
13
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
0
13
13
13
0
0
0
0
13
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
38
0
0
0
0
25
13
25
0
0
13
0
% I
% Lys:
13
0
0
13
13
13
0
0
13
25
0
0
25
25
0
% K
% Leu:
0
0
25
13
25
25
0
13
0
13
0
13
13
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
25
0
13
0
38
25
0
0
% N
% Pro:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
25
0
25
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
13
13
0
0
0
0
13
0
0
13
0
% R
% Ser:
13
38
0
0
0
0
25
0
38
0
13
0
13
0
25
% S
% Thr:
0
0
0
0
0
13
13
13
0
0
0
0
0
0
0
% T
% Val:
0
13
13
0
0
0
0
13
13
25
13
0
0
13
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _