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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPM1J All Species: 17.27
Human Site: S135 Identified Species: 34.55
UniProt: Q5JR12 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JR12 NP_005158.5 505 54834 S135 V Y V E G R R S V T G V P R E
Chimpanzee Pan troglodytes XP_513628 505 54871 S135 V Y V E G R R S V T G V P R E
Rhesus Macaque Macaca mulatta XP_001096598 450 48605 Y129 Q A C C E V V Y V E G R R S V
Dog Lupus familis XP_540335 509 54913 S139 V Y V E G R R S V S G A P R E
Cat Felis silvestris
Mouse Mus musculus Q149T7 507 55531 S134 V Y V E S R R S R S V T G V S
Rat Rattus norvegicus Q641Y6 504 55192 S134 V Y V E S R R S I T G V S R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507685 606 67811 L136 L R D L V E I L Q D P A P P P
Chicken Gallus gallus XP_418000 495 54949 G134 G S G E P D R G R K G F Y F H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q05AL2 516 56543 Q168 L H I E E Q L Q E V L E I L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608468 651 72868 T135 K H P D L P Y T Y F G I F D G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798783 601 66691 R218 M F I N N K H R E K T L D T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49598 399 43332 E78 L D S N V R S E N K K A R S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 85.5 93.1 N.A. 88.3 88.3 N.A. 56.1 68.5 N.A. 47.2 N.A. 30.8 N.A. N.A. 36.1
Protein Similarity: 100 100 86.7 96.2 N.A. 91.3 90.6 N.A. 63.2 77 N.A. 62 N.A. 45 N.A. N.A. 51.2
P-Site Identity: 100 100 13.3 86.6 N.A. 46.6 80 N.A. 6.6 20 N.A. 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 13.3 93.3 N.A. 53.3 86.6 N.A. 13.3 20 N.A. 40 N.A. 33.3 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 22.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 0 0 25 0 0 9 % A
% Cys: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 9 0 9 0 0 0 9 0 0 9 9 0 % D
% Glu: 0 0 0 59 17 9 0 9 17 9 0 9 0 0 34 % E
% Phe: 0 9 0 0 0 0 0 0 0 9 0 9 9 9 0 % F
% Gly: 9 0 9 0 25 0 0 9 0 0 59 0 9 0 9 % G
% His: 0 17 0 0 0 0 9 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 17 0 0 0 9 0 9 0 0 9 9 0 0 % I
% Lys: 9 0 0 0 0 9 0 0 0 25 9 0 0 0 0 % K
% Leu: 25 0 0 9 9 0 9 9 0 0 9 9 0 9 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 9 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 9 9 0 0 0 0 9 0 34 9 9 % P
% Gln: 9 0 0 0 0 9 0 9 9 0 0 0 0 0 9 % Q
% Arg: 0 9 0 0 0 50 50 9 17 0 0 9 17 34 0 % R
% Ser: 0 9 9 0 17 0 9 42 0 17 0 0 9 17 17 % S
% Thr: 0 0 0 0 0 0 0 9 0 25 9 9 0 9 0 % T
% Val: 42 0 42 0 17 9 9 0 34 9 9 25 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 42 0 0 0 0 9 9 9 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _