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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTUS2 All Species: 17.27
Human Site: S46 Identified Species: 38
UniProt: Q5JR59 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JR59 NP_001028774.2 1369 150195 S46 Q I M L E V S S S H D E S K T
Chimpanzee Pan troglodytes XP_509608 1379 151159 S56 Q I M L E V S S S H D E S K T
Rhesus Macaque Macaca mulatta XP_001117981 1204 130179 A31 Q L R D N R N A A R N N N E S
Dog Lupus familis XP_543149 1380 150297 S46 Q I M L E V S S S H D E S E T
Cat Felis silvestris
Mouse Mus musculus Q3UHD3 1353 147337 S46 Q I M L E V S S S C D E A K S
Rat Rattus norvegicus NP_001094459 315 36890
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519664 1610 171417 L71 L L I E A V C L G L V G G G Y
Chicken Gallus gallus XP_417117 1396 154111 T46 Q I V S K V R T M E G D I K K
Frog Xenopus laevis Q7SZL5 1338 147049 P46 A N V N D Q G P G V I D H S I
Zebra Danio Brachydanio rerio XP_684038 1302 144773 V53 D R E N D S S V P M S H S E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200114 1595 177229 T62 P P H L V P S T P N V P F R H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 79.4 77.4 N.A. 69.6 21.1 N.A. 31.4 48.1 21.6 33.6 N.A. N.A. N.A. N.A. 20.8
Protein Similarity: 100 98.5 82 83.4 N.A. 79.4 22.3 N.A. 44.8 63.4 40.5 48.5 N.A. N.A. N.A. N.A. 39.4
P-Site Identity: 100 100 6.6 93.3 N.A. 80 0 N.A. 6.6 26.6 0 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 60 100 N.A. 93.3 0 N.A. 20 53.3 20 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 10 10 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % C
% Asp: 10 0 0 10 19 0 0 0 0 0 37 19 0 0 0 % D
% Glu: 0 0 10 10 37 0 0 0 0 10 0 37 0 28 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 19 0 10 10 10 10 0 % G
% His: 0 0 10 0 0 0 0 0 0 28 0 10 10 0 10 % H
% Ile: 0 46 10 0 0 0 0 0 0 0 10 0 10 0 10 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 37 10 % K
% Leu: 10 19 0 46 0 0 0 10 0 10 0 0 0 0 0 % L
% Met: 0 0 37 0 0 0 0 0 10 10 0 0 0 0 0 % M
% Asn: 0 10 0 19 10 0 10 0 0 10 10 10 10 0 0 % N
% Pro: 10 10 0 0 0 10 0 10 19 0 0 10 0 0 0 % P
% Gln: 55 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 10 10 0 0 10 0 0 0 10 0 % R
% Ser: 0 0 0 10 0 10 55 37 37 0 10 0 37 10 19 % S
% Thr: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 28 % T
% Val: 0 0 19 0 10 55 0 10 0 10 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _