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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIA3 All Species: 6.97
Human Site: S678 Identified Species: 19.17
UniProt: Q5JRA6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JRA6 NP_940953.2 1907 213702 S678 M S E K I R L S E G E A K E D
Chimpanzee Pan troglodytes XP_514216 1807 202464 S677 M S E K I R L S E G E A K D D
Rhesus Macaque Macaca mulatta XP_001100730 1906 212908 E680 S E K I R L S E G E A E E D S
Dog Lupus familis XP_536152 1858 205630 A644 D S S A E E L A P Q Q P K A G
Cat Felis silvestris
Mouse Mus musculus Q8BI84 1930 213656 E656 N E K T G F P E E E S R E D G
Rat Rattus norvegicus XP_001064186 1920 212989 E665 F P E E E G R E D L T D A E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512120 2084 231152 S744 E S Y K S P E S M L L E D K E
Chicken Gallus gallus XP_419399 1290 142882 L218 H L P E S I L L G D S E E I Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMA7 1430 159034 S358 E V S K Q E D S S L P T E T L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 92.8 72.6 N.A. 63.5 63.1 N.A. 45.5 34.4 N.A. N.A. N.A. 21.6 N.A. N.A. N.A.
Protein Similarity: 100 94.1 95.8 80.9 N.A. 75.8 75.6 N.A. 61.7 47.2 N.A. N.A. N.A. 38.4 N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 20 N.A. 6.6 13.3 N.A. 20 6.6 N.A. N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 33.3 N.A. 26.6 26.6 N.A. 33.3 20 N.A. N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 12 0 0 12 23 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 12 0 12 12 0 12 12 34 23 % D
% Glu: 23 23 34 23 23 23 12 34 34 23 23 34 45 23 12 % E
% Phe: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 12 0 0 23 23 0 0 0 0 23 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 23 12 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 23 45 0 0 0 0 0 0 0 0 34 12 0 % K
% Leu: 0 12 0 0 0 12 45 12 0 34 12 0 0 0 12 % L
% Met: 23 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 12 0 0 12 12 0 12 0 12 12 0 0 12 % P
% Gln: 0 0 0 0 12 0 0 0 0 12 12 0 0 0 12 % Q
% Arg: 0 0 0 0 12 23 12 0 0 0 0 12 0 0 0 % R
% Ser: 12 45 23 0 23 0 12 45 12 0 23 0 0 0 12 % S
% Thr: 0 0 0 12 0 0 0 0 0 0 12 12 0 12 0 % T
% Val: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _