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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM70A All Species: 17.27
Human Site: S146 Identified Species: 47.5
UniProt: Q5JRV8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JRV8 NP_001098014.1 349 38449 S146 A E E V I S S S T K N S P S T
Chimpanzee Pan troglodytes XP_001169393 229 24274 G27 V P L T P P A G R V L A P E P
Rhesus Macaque Macaca mulatta XP_001085757 349 38490 S146 A E E V I S S S T K N S P S T
Dog Lupus familis XP_538157 349 38244 S146 A E E V I S S S T K N S P S A
Cat Felis silvestris
Mouse Mus musculus Q8BHW5 351 38615 S146 A E E V I T S S S K I T P S T
Rat Rattus norvegicus Q7TMP6 351 38598 S146 A E E V I T S S S K I T P S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509879 345 37922 C142 P Q K E I E E C L P N H P P F
Chicken Gallus gallus XP_420338 322 35323 L120 F A A R H I D L R P L Y A G R
Frog Xenopus laevis Q66IQ1 321 35264 L119 F A A R H L D L R P L Y A G K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.5 99.4 98.2 N.A. 94.8 95.1 N.A. 82.8 78.8 66.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.8 99.4 98.5 N.A. 96.8 96.5 N.A. 88.8 85 75.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 73.3 73.3 N.A. 20 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 93.3 93.3 N.A. 33.3 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 23 23 0 0 0 12 0 0 0 0 12 23 0 12 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % D
% Glu: 0 56 56 12 0 12 12 0 0 0 0 0 0 12 0 % E
% Phe: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 0 23 0 % G
% His: 0 0 0 0 23 0 0 0 0 0 0 12 0 0 0 % H
% Ile: 0 0 0 0 67 12 0 0 0 0 23 0 0 0 0 % I
% Lys: 0 0 12 0 0 0 0 0 0 56 0 0 0 0 12 % K
% Leu: 0 0 12 0 0 12 0 23 12 0 34 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 % N
% Pro: 12 12 0 0 12 12 0 0 0 34 0 0 78 12 12 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 23 0 0 0 0 34 0 0 0 0 0 12 % R
% Ser: 0 0 0 0 0 34 56 56 23 0 0 34 0 56 0 % S
% Thr: 0 0 0 12 0 23 0 0 34 0 0 23 0 0 45 % T
% Val: 12 0 0 56 0 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _