Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PITRM1 All Species: 33.94
Human Site: S286 Identified Species: 49.78
UniProt: Q5JRX3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JRX3 NP_055704.2 1037 117455 S286 Q I H E E A L S K F Q K I E P
Chimpanzee Pan troglodytes XP_001140483 1037 117419 S286 Q I H E E A L S K F Q K I E P
Rhesus Macaque Macaca mulatta XP_001102165 1037 117178 S286 Q I H E E A L S K F Q K I E P
Dog Lupus familis XP_535200 1034 116597 S284 Q I H K E A L S K F E K I E T
Cat Felis silvestris
Mouse Mus musculus Q8K411 1036 117353 S286 Q I H E E A L S K F Q R L E Q
Rat Rattus norvegicus NP_001100833 954 108526 N261 T T H Y H P S N A R F F T Y G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511135 1062 120280 S312 Q I H E E A L S K F Q R I E P
Chicken Gallus gallus XP_418564 1033 117297 V283 Q I H E E A L V K F E R I E S
Frog Xenopus laevis Q6PF24 1027 116662 S280 Q I H E D A L S K F G R I D P
Zebra Danio Brachydanio rerio Q7ZVZ6 1023 114953 S281 Q I E E E A M S K F E R T E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9E3 1034 119306 D311 L D E E Y L S D Q S W V D N S
Honey Bee Apis mellifera XP_397099 1006 116139 L269 I N E R Y L F L M D N I D T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792865 1008 113372 S286 L I E E K A L S H F E R L Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJL3 1080 120996 M343 V L S E Y L D M F E A S P S P
Baker's Yeast Sacchar. cerevisiae P32898 989 112162 L274 R A R K D K L L M P I D L K K
Red Bread Mold Neurospora crassa Q7S7C0 1012 112806 D273 K E I G A Q L D V F E K I R A
Conservation
Percent
Protein Identity: 100 99.3 97.8 82.2 N.A. 86.5 78.6 N.A. 79.8 76.7 72.9 67.5 N.A. 38.6 44.3 N.A. 51
Protein Similarity: 100 99.9 98.9 90.8 N.A. 93.9 86.2 N.A. 88.4 87.5 85.7 82.4 N.A. 57.9 63.5 N.A. 68.5
P-Site Identity: 100 100 100 80 N.A. 80 6.6 N.A. 93.3 73.3 73.3 66.6 N.A. 6.6 0 N.A. 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. 100 86.6 93.3 86.6 N.A. 13.3 0 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 30.2 35.1 39.6
Protein Similarity: N.A. N.A. N.A. 48.7 54.7 57.8
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. 20 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 63 0 0 7 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 13 0 7 13 0 7 0 7 13 7 0 % D
% Glu: 0 7 25 69 50 0 0 0 0 7 32 0 0 50 0 % E
% Phe: 0 0 0 0 0 0 7 0 7 69 7 7 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 7 % G
% His: 0 0 57 0 7 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 63 7 0 0 0 0 0 0 0 7 7 50 0 0 % I
% Lys: 7 0 0 13 7 7 0 0 57 0 0 32 0 7 7 % K
% Leu: 13 7 0 0 0 19 69 13 0 0 0 0 19 0 0 % L
% Met: 0 0 0 0 0 0 7 7 13 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 7 0 0 7 0 0 7 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 7 0 0 7 0 50 % P
% Gln: 57 0 0 0 0 7 0 0 7 0 32 0 0 7 7 % Q
% Arg: 7 0 7 7 0 0 0 0 0 7 0 38 0 7 0 % R
% Ser: 0 0 7 0 0 0 13 57 0 7 0 7 0 7 19 % S
% Thr: 7 7 0 0 0 0 0 0 0 0 0 0 13 7 7 % T
% Val: 7 0 0 0 0 0 0 7 7 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 7 19 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _