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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITRM1
All Species:
32.12
Human Site:
S649
Identified Species:
47.11
UniProt:
Q5JRX3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JRX3
NP_055704.2
1037
117455
S649
K
T
G
G
M
S
A
S
P
H
V
L
P
D
D
Chimpanzee
Pan troglodytes
XP_001140483
1037
117419
S649
K
T
G
G
M
S
A
S
P
H
V
L
P
D
D
Rhesus Macaque
Macaca mulatta
XP_001102165
1037
117178
S649
K
T
G
G
M
S
A
S
P
H
V
L
P
D
D
Dog
Lupus familis
XP_535200
1034
116597
S647
K
T
G
G
M
T
V
S
P
H
V
L
P
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K411
1036
117353
T649
K
T
G
G
M
S
V
T
P
H
V
L
P
D
D
Rat
Rattus norvegicus
NP_001100833
954
108526
F586
T
Y
E
Q
G
V
L
F
S
S
L
C
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511135
1062
120280
S675
K
T
G
G
M
S
V
S
P
H
V
I
P
D
D
Chicken
Gallus gallus
XP_418564
1033
117297
S646
K
T
G
G
M
S
V
S
P
H
I
I
P
D
D
Frog
Xenopus laevis
Q6PF24
1027
116662
C642
T
T
G
G
M
S
V
C
P
H
I
I
S
D
D
Zebra Danio
Brachydanio rerio
Q7ZVZ6
1023
114953
S643
K
T
G
G
L
S
V
S
P
Q
I
I
P
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9E3
1034
119306
T652
V
I
S
A
M
G
T
T
N
Y
N
Y
R
E
F
Honey Bee
Apis mellifera
XP_397099
1006
116139
F617
K
N
Y
D
Y
R
N
F
D
Q
M
I
R
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792865
1008
113372
G627
V
I
T
K
M
G
A
G
E
L
D
F
I
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJL3
1080
120996
T691
Q
S
L
L
E
M
G
T
K
D
L
T
F
V
Q
Baker's Yeast
Sacchar. cerevisiae
P32898
989
112162
I606
T
T
E
S
F
S
E
I
E
D
Q
I
K
L
H
Red Bread Mold
Neurospora crassa
Q7S7C0
1012
112806
K620
S
I
M
R
L
G
T
K
D
M
T
M
E
Q
L
Conservation
Percent
Protein Identity:
100
99.3
97.8
82.2
N.A.
86.5
78.6
N.A.
79.8
76.7
72.9
67.5
N.A.
38.6
44.3
N.A.
51
Protein Similarity:
100
99.9
98.9
90.8
N.A.
93.9
86.2
N.A.
88.4
87.5
85.7
82.4
N.A.
57.9
63.5
N.A.
68.5
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
86.6
80
60
60
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
93.3
93.3
73.3
80
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
35.1
39.6
Protein Similarity:
N.A.
N.A.
N.A.
48.7
54.7
57.8
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
25
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
13
13
7
0
0
57
50
% D
% Glu:
0
0
13
0
7
0
7
0
13
0
0
0
7
19
0
% E
% Phe:
0
0
0
0
7
0
0
13
0
0
0
7
7
0
13
% F
% Gly:
0
0
57
57
7
19
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
7
% H
% Ile:
0
19
0
0
0
0
0
7
0
0
19
38
7
0
0
% I
% Lys:
57
0
0
7
0
0
0
7
7
0
0
0
7
0
7
% K
% Leu:
0
0
7
7
13
0
7
0
0
7
13
32
7
13
7
% L
% Met:
0
0
7
0
63
7
0
0
0
7
7
7
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
7
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
57
0
0
0
50
0
0
% P
% Gln:
7
0
0
7
0
0
0
0
0
13
7
0
0
7
7
% Q
% Arg:
0
0
0
7
0
7
0
0
0
0
0
0
13
0
7
% R
% Ser:
7
7
7
7
0
57
0
44
7
7
0
0
7
0
0
% S
% Thr:
19
63
7
0
0
7
13
19
0
0
7
7
0
0
7
% T
% Val:
13
0
0
0
0
7
38
0
0
0
38
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
7
0
0
0
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _