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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGD3
All Species:
4.24
Human Site:
T510
Identified Species:
11.67
UniProt:
Q5JSP0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JSP0
NP_001077005.1
725
79401
T510
S
P
V
E
P
V
V
T
T
E
G
S
S
G
A
Chimpanzee
Pan troglodytes
XP_520721
853
95715
V649
R
W
I
R
D
N
E
V
T
M
C
M
K
C
K
Rhesus Macaque
Macaca mulatta
XP_001104022
725
79405
T510
S
P
L
E
S
V
V
T
T
E
G
S
S
G
A
Dog
Lupus familis
XP_541329
735
79963
A519
S
P
E
E
P
A
L
A
A
S
G
G
G
G
V
Cat
Felis silvestris
Mouse
Mus musculus
O88842
733
80605
V506
S
S
V
E
P
A
G
V
A
D
S
N
G
G
T
Rat
Rattus norvegicus
O88387
766
86435
V562
R
W
I
R
D
N
E
V
T
M
C
M
K
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514995
366
41694
K162
L
L
K
D
Y
L
K
K
L
P
G
E
S
P
D
Chicken
Gallus gallus
XP_414331
761
85208
D542
V
E
S
M
P
G
A
D
S
G
A
F
G
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688794
945
105983
R725
K
R
A
P
T
P
I
R
E
K
E
V
T
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.3
95.4
71.1
N.A.
74.9
41.9
N.A.
41.2
60.1
N.A.
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.7
97
78.5
N.A.
82.1
58.6
N.A.
46.6
72.4
N.A.
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
40
N.A.
33.3
6.6
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
46.6
N.A.
46.6
13.3
N.A.
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
23
12
12
23
0
12
0
0
0
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
23
0
0
23
12
% C
% Asp:
0
0
0
12
23
0
0
12
0
12
0
0
0
0
12
% D
% Glu:
0
12
12
45
0
0
23
0
12
23
12
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
12
12
0
0
12
45
12
34
56
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
12
12
0
12
0
0
23
0
23
% K
% Leu:
12
12
12
0
0
12
12
0
12
0
0
0
0
12
0
% L
% Met:
0
0
0
12
0
0
0
0
0
23
0
23
0
0
0
% M
% Asn:
0
0
0
0
0
23
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
34
0
12
45
12
0
0
0
12
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
23
12
0
23
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
45
12
12
0
12
0
0
0
12
12
12
23
34
0
12
% S
% Thr:
0
0
0
0
12
0
0
23
45
0
0
0
12
0
12
% T
% Val:
12
0
23
0
0
23
23
34
0
0
0
12
0
0
12
% V
% Trp:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _