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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHC2
All Species:
4.55
Human Site:
T218
Identified Species:
11.11
UniProt:
Q5JST6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JST6
NP_079460.2
749
87397
T218
R
P
Y
E
S
L
D
T
L
K
Q
F
L
Q
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097580
735
86010
T204
R
P
Y
E
S
L
D
T
L
K
Q
F
L
Q
Y
Dog
Lupus familis
XP_538007
779
90137
D248
L
R
P
Y
E
S
F
D
T
L
K
Q
F
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D485
750
87628
D217
F
R
P
Y
Q
S
F
D
T
L
K
R
F
I
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512633
814
92626
I281
P
F
R
P
Y
E
H
I
D
T
L
G
Q
F
L
Chicken
Gallus gallus
Q32TG3
746
86643
I216
P
L
R
P
Y
E
R
I
D
T
L
K
Q
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q32TF8
748
85439
R215
K
P
L
R
P
Y
E
R
L
D
T
L
K
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611459
765
88083
K227
T
A
T
S
A
L
P
K
K
H
A
F
A
Q
F
Honey Bee
Apis mellifera
XP_396096
750
88874
P205
Q
E
R
F
P
K
N
P
K
R
T
I
D
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798540
744
85632
K214
Q
P
L
R
P
Y
E
K
V
D
T
L
K
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.8
74.3
N.A.
74.1
N.A.
N.A.
55.2
56.4
N.A.
53
N.A.
33.4
35.3
N.A.
47.1
Protein Similarity:
100
N.A.
95.4
83.6
N.A.
85.5
N.A.
N.A.
70.8
73.6
N.A.
70.4
N.A.
54.2
58.1
N.A.
65.1
P-Site Identity:
100
N.A.
100
0
N.A.
0
N.A.
N.A.
0
0
N.A.
20
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
N.A.
100
6.6
N.A.
6.6
N.A.
N.A.
0
0
N.A.
40
N.A.
33.3
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
20
20
20
0
0
10
0
0
% D
% Glu:
0
10
0
20
10
20
20
0
0
0
0
0
0
0
10
% E
% Phe:
10
10
0
10
0
0
20
0
0
0
0
30
20
20
30
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
20
0
0
0
10
0
10
0
% I
% Lys:
10
0
0
0
0
10
0
20
20
20
20
10
20
0
0
% K
% Leu:
10
10
20
0
0
30
0
0
30
20
20
20
20
10
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
20
40
20
20
30
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
20
0
0
0
10
0
0
0
0
0
20
10
20
50
10
% Q
% Arg:
20
20
30
20
0
0
10
10
0
10
0
10
0
0
0
% R
% Ser:
0
0
0
10
20
20
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
20
20
20
30
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
20
20
20
0
0
0
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _