KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHC2
All Species:
21.21
Human Site:
Y196
Identified Species:
51.85
UniProt:
Q5JST6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JST6
NP_079460.2
749
87397
Y196
V
Q
C
P
E
D
P
Y
M
K
I
R
R
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097580
735
86010
Y182
V
P
C
P
E
D
P
Y
M
K
I
R
R
E
V
Dog
Lupus familis
XP_538007
779
90137
Y227
G
Q
C
P
E
D
P
Y
M
K
I
R
R
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D485
750
87628
Y196
G
Q
C
P
L
D
P
Y
M
K
M
R
R
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512633
814
92626
Y261
V
F
C
P
E
D
P
Y
M
K
E
R
K
K
V
Chicken
Gallus gallus
Q32TG3
746
86643
Y196
G
N
R
P
D
D
P
Y
T
K
E
R
Q
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q32TF8
748
85439
P192
L
N
P
P
A
S
T
P
A
D
P
Y
T
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611459
765
88083
T205
Q
Q
E
P
C
D
P
T
T
E
I
R
K
R
S
Honey Bee
Apis mellifera
XP_396096
750
88874
E185
I
P
V
P
D
P
I
E
I
P
K
D
P
H
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798540
744
85632
P191
I
K
A
P
A
E
T
P
K
D
P
Y
T
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.8
74.3
N.A.
74.1
N.A.
N.A.
55.2
56.4
N.A.
53
N.A.
33.4
35.3
N.A.
47.1
Protein Similarity:
100
N.A.
95.4
83.6
N.A.
85.5
N.A.
N.A.
70.8
73.6
N.A.
70.4
N.A.
54.2
58.1
N.A.
65.1
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
73.3
N.A.
N.A.
73.3
40
N.A.
6.6
N.A.
40
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
80
N.A.
N.A.
86.6
66.6
N.A.
20
N.A.
53.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
20
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
50
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
70
0
0
0
20
0
10
0
0
0
% D
% Glu:
0
0
10
0
40
10
0
10
0
10
20
0
0
40
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
30
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
20
0
0
0
0
0
10
0
10
0
40
0
0
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
10
60
10
0
20
20
0
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
50
0
10
0
0
0
10
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
20
10
100
0
10
70
20
0
10
20
0
10
0
0
% P
% Gln:
10
40
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
70
40
10
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
20
10
20
0
0
0
20
10
20
% T
% Val:
30
0
10
0
0
0
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _