KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHC2
All Species:
5.15
Human Site:
Y213
Identified Species:
12.59
UniProt:
Q5JST6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JST6
NP_079460.2
749
87397
Y213
H
V
E
P
L
R
P
Y
E
S
L
D
T
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097580
735
86010
Y199
H
V
E
P
L
R
P
Y
E
S
L
D
T
L
K
Dog
Lupus familis
XP_538007
779
90137
P243
D
C
M
K
P
L
R
P
Y
E
S
F
D
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D485
750
87628
P212
E
F
V
D
P
F
R
P
Y
Q
S
F
D
T
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512633
814
92626
R276
T
D
K
M
N
P
F
R
P
Y
E
H
I
D
T
Chicken
Gallus gallus
Q32TG3
746
86643
R211
L
D
S
M
N
P
L
R
P
Y
E
R
I
D
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q32TF8
748
85439
L210
L
E
E
N
M
K
P
L
R
P
Y
E
R
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611459
765
88083
T222
K
Q
T
G
N
T
A
T
S
A
L
P
K
K
H
Honey Bee
Apis mellifera
XP_396096
750
88874
R200
E
L
H
K
Q
Q
E
R
F
P
K
N
P
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798540
744
85632
L209
M
D
E
A
Q
Q
P
L
R
P
Y
E
K
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.8
74.3
N.A.
74.1
N.A.
N.A.
55.2
56.4
N.A.
53
N.A.
33.4
35.3
N.A.
47.1
Protein Similarity:
100
N.A.
95.4
83.6
N.A.
85.5
N.A.
N.A.
70.8
73.6
N.A.
70.4
N.A.
54.2
58.1
N.A.
65.1
P-Site Identity:
100
N.A.
100
0
N.A.
0
N.A.
N.A.
0
0
N.A.
20
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
N.A.
100
0
N.A.
0
N.A.
N.A.
6.6
0
N.A.
40
N.A.
13.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
30
0
10
0
0
0
0
0
0
0
20
20
20
20
% D
% Glu:
20
10
40
0
0
0
10
0
20
10
20
20
0
0
0
% E
% Phe:
0
10
0
0
0
10
10
0
10
0
0
20
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
20
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
10
0
10
20
0
10
0
0
0
0
10
0
20
20
20
% K
% Leu:
20
10
0
0
20
10
10
20
0
0
30
0
0
30
20
% L
% Met:
10
0
10
20
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
30
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
20
20
20
40
20
20
30
0
10
10
0
0
% P
% Gln:
0
10
0
0
20
20
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
20
30
20
0
0
10
10
0
10
% R
% Ser:
0
0
10
0
0
0
0
0
10
20
20
0
0
0
0
% S
% Thr:
10
0
10
0
0
10
0
10
0
0
0
0
20
20
20
% T
% Val:
0
20
10
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
20
20
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _