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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHC2
All Species:
20
Human Site:
Y97
Identified Species:
48.89
UniProt:
Q5JST6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JST6
NP_079460.2
749
87397
Y97
L
D
K
S
Q
T
N
Y
R
I
R
Y
Y
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097580
735
86010
K89
N
Y
R
I
R
Y
Y
K
I
Y
F
Y
P
E
D
Dog
Lupus familis
XP_538007
779
90137
Y128
P
D
K
S
Q
G
N
Y
R
I
R
R
Y
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D485
750
87628
F97
S
D
K
R
Q
E
I
F
R
I
R
Y
Y
K
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512633
814
92626
Y162
P
D
K
N
Q
E
L
Y
R
I
R
H
C
K
I
Chicken
Gallus gallus
Q32TG3
746
86643
Y97
P
D
K
N
Q
E
P
Y
R
I
R
H
C
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q32TF8
748
85439
Y97
P
Q
R
R
E
E
K
Y
R
V
R
K
C
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611459
765
88083
Y106
T
E
I
Y
H
A
P
Y
Q
V
R
K
V
K
I
Honey Bee
Apis mellifera
XP_396096
750
88874
Y92
V
H
E
R
N
T
A
Y
Q
V
R
V
V
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798540
744
85632
Y96
V
H
E
M
R
Q
Q
Y
R
I
R
K
C
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.8
74.3
N.A.
74.1
N.A.
N.A.
55.2
56.4
N.A.
53
N.A.
33.4
35.3
N.A.
47.1
Protein Similarity:
100
N.A.
95.4
83.6
N.A.
85.5
N.A.
N.A.
70.8
73.6
N.A.
70.4
N.A.
54.2
58.1
N.A.
65.1
P-Site Identity:
100
N.A.
6.6
80
N.A.
66.6
N.A.
N.A.
60
60
N.A.
33.3
N.A.
26.6
26.6
N.A.
40
P-Site Similarity:
100
N.A.
26.6
80
N.A.
73.3
N.A.
N.A.
73.3
73.3
N.A.
53.3
N.A.
46.6
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% C
% Asp:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
20
0
10
40
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
20
0
0
10
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
0
10
10
0
0
10
0
10
60
0
0
0
0
90
% I
% Lys:
0
0
50
0
0
0
10
10
0
0
0
30
0
80
0
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
20
10
0
20
0
0
0
0
0
0
10
0
% N
% Pro:
40
0
0
0
0
0
20
0
0
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
50
10
10
0
20
0
0
0
0
0
0
% Q
% Arg:
0
0
20
30
20
0
0
0
70
0
90
10
0
0
0
% R
% Ser:
10
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
0
0
0
30
0
10
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
10
10
80
0
10
0
30
30
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _