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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM123B
All Species:
9.7
Human Site:
Y445
Identified Species:
30.48
UniProt:
Q5JTC6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JTC6
NP_689637.3
1135
124029
Y445
L
L
D
P
V
R
S
Y
P
G
L
A
P
G
E
Chimpanzee
Pan troglodytes
XP_521092
1101
120262
Y446
L
L
D
P
V
R
S
Y
P
G
L
A
P
G
E
Rhesus Macaque
Macaca mulatta
XP_001096922
803
87524
M162
V
A
E
K
V
P
S
M
P
K
P
K
K
G
L
Dog
Lupus familis
XP_848346
1130
123421
Y442
L
L
D
S
V
R
S
Y
P
G
L
A
P
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS75
1125
123242
H439
F
N
M
N
L
G
Y
H
T
A
I
S
P
S
H
Rat
Rattus norvegicus
NP_001102790
1111
121671
H427
F
N
M
N
L
G
Y
H
T
A
I
S
P
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420290
1143
123670
S449
G
E
V
H
P
Y
A
S
G
A
V
D
G
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341956
953
105058
V311
I
I
A
D
Q
D
D
V
S
V
A
E
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
67.6
82.6
N.A.
79.4
79.3
N.A.
N.A.
38.1
N.A.
27
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
68.7
87.9
N.A.
84.6
84.7
N.A.
N.A.
51.1
N.A.
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
93.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
93.3
N.A.
33.3
33.3
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
0
0
0
13
0
0
38
13
38
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
38
13
0
13
13
0
0
0
0
13
0
0
0
% D
% Glu:
0
13
13
0
0
0
0
0
0
0
0
13
0
0
50
% E
% Phe:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
25
0
0
13
38
0
0
13
50
0
% G
% His:
0
0
0
13
0
0
0
25
0
0
0
0
0
0
25
% H
% Ile:
13
13
0
0
0
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
13
0
0
0
0
0
13
0
13
13
0
0
% K
% Leu:
38
38
0
0
25
0
0
0
0
0
38
0
0
0
13
% L
% Met:
0
0
25
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
25
0
25
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
25
13
13
0
0
50
0
13
0
63
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
0
0
50
13
13
0
0
25
13
38
0
% S
% Thr:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% T
% Val:
13
0
13
0
50
0
0
13
0
13
13
0
0
13
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
25
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _