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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf117
All Species:
10
Human Site:
S495
Identified Species:
27.5
UniProt:
Q5JU67
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JU67
NP_001012520.2
520
60533
S495
G
T
F
R
A
H
S
S
P
E
M
R
A
P
G
Chimpanzee
Pan troglodytes
XP_001143084
605
69321
R581
R
L
L
S
Y
I
T
R
V
G
T
F
R
A
H
Rhesus Macaque
Macaca mulatta
XP_001095281
521
60354
S496
G
T
F
R
A
H
S
S
P
E
I
R
A
P
A
Dog
Lupus familis
XP_537834
530
61028
R505
G
I
F
Q
V
H
S
R
P
E
I
H
T
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q0VFX2
523
61030
E500
G
I
C
Q
N
T
N
E
I
Y
P
S
G
A
L
Rat
Rattus norvegicus
Q4V7B0
542
62773
T502
G
I
C
K
L
Q
N
T
T
E
I
Y
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516541
666
75047
S514
A
T
S
R
R
R
A
S
W
F
S
T
A
M
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BDR7
471
54177
R447
G
D
L
G
L
V
P
R
K
T
H
S
T
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783013
565
64219
T492
S
S
F
P
S
D
R
T
R
Q
L
S
A
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
95.1
72.8
N.A.
64.8
64.2
N.A.
43.6
N.A.
N.A.
35.1
N.A.
N.A.
N.A.
N.A.
38.2
Protein Similarity:
100
82.4
96.3
82.4
N.A.
79.3
78.4
N.A.
57.6
N.A.
N.A.
55.9
N.A.
N.A.
N.A.
N.A.
58.2
P-Site Identity:
100
0
86.6
46.6
N.A.
6.6
20
N.A.
26.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
93.3
60
N.A.
20
46.6
N.A.
33.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
23
0
12
0
0
0
0
0
45
23
12
% A
% Cys:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
45
0
0
0
0
0
% E
% Phe:
0
0
45
0
0
0
0
0
0
12
0
12
0
0
0
% F
% Gly:
67
0
0
12
0
0
0
0
0
12
0
0
12
0
34
% G
% His:
0
0
0
0
0
34
0
0
0
0
12
12
0
0
12
% H
% Ile:
0
34
0
0
0
12
0
0
12
0
34
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
12
23
0
23
0
0
0
0
0
12
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% M
% Asn:
0
0
0
0
12
0
23
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
12
0
34
0
12
0
12
23
12
% P
% Gln:
0
0
0
23
0
12
0
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
0
34
12
12
12
34
12
0
0
23
12
0
0
% R
% Ser:
12
12
12
12
12
0
34
34
0
0
12
34
0
34
12
% S
% Thr:
0
34
0
0
0
12
12
23
12
12
12
12
23
12
12
% T
% Val:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _