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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQSEC2
All Species:
6.06
Human Site:
S268
Identified Species:
14.81
UniProt:
Q5JU85
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JU85
NP_001104595.1
1478
161736
S268
L
S
Q
L
P
P
S
S
S
H
M
G
G
P
P
Chimpanzee
Pan troglodytes
XP_516294
1034
115556
Rhesus Macaque
Macaca mulatta
XP_001083503
963
108344
Dog
Lupus familis
XP_549015
1288
142879
Y206
G
R
E
K
E
A
G
Y
S
V
A
V
G
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU25
1478
161832
S268
L
S
Q
L
P
P
T
S
S
H
M
G
G
P
P
Rat
Rattus norvegicus
Q76M68
1194
129000
H111
P
E
P
P
L
Q
H
H
G
Q
L
L
A
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507072
628
70367
Chicken
Gallus gallus
XP_414318
1243
140561
S161
A
Y
G
L
Y
S
V
S
P
G
Q
Q
R
T
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337643
1379
150607
G240
E
G
I
G
D
V
S
G
V
V
D
D
F
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396854
1053
118476
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
40.8
74.6
N.A.
98.9
34.5
N.A.
28.3
46.8
N.A.
44.5
N.A.
N.A.
28.8
N.A.
N.A.
Protein Similarity:
100
51.1
49.9
77.2
N.A.
99.4
46.8
N.A.
33
58
N.A.
53.9
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
100
0
0
13.3
N.A.
93.3
6.6
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
0
0
20
N.A.
100
13.3
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
10
10
0
0
0
% D
% Glu:
10
10
10
0
10
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
10
10
10
0
0
10
10
10
10
0
20
30
10
10
% G
% His:
0
0
0
0
0
0
10
10
0
20
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
20
0
0
30
10
0
0
0
0
0
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
10
20
20
0
0
10
0
0
0
0
20
30
% P
% Gln:
0
0
20
0
0
10
0
0
0
10
10
10
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
0
20
0
0
0
10
20
30
30
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
10
10
0
10
20
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _