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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHC1
All Species:
22.12
Human Site:
Y123
Identified Species:
54.07
UniProt:
Q5JVL4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JVL4
NP_060570.2
640
73990
Y123
R
I
R
Q
V
N
I
Y
Y
Y
L
E
D
D
S
Chimpanzee
Pan troglodytes
XP_001152433
640
73974
Y123
R
I
R
Q
V
N
I
Y
Y
Y
L
E
D
D
S
Rhesus Macaque
Macaca mulatta
XP_001107280
640
73892
Y123
R
I
R
Q
V
N
I
Y
Y
Y
L
E
D
D
S
Dog
Lupus familis
XP_532170
810
92443
Y292
R
I
R
Q
V
N
I
Y
Y
Y
L
E
D
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9T8
648
75123
Y123
R
I
R
H
V
N
I
Y
Y
Y
L
E
D
D
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510138
647
75030
Y129
R
V
R
Q
M
G
I
Y
Y
F
L
E
D
D
S
Chicken
Gallus gallus
Q32TG3
746
86643
I113
F
Y
L
E
D
D
T
I
Q
V
L
E
P
Q
V
Frog
Xenopus laevis
NP_001086409
552
63835
K94
P
S
Y
V
A
F
D
K
K
V
L
R
F
E
G
Zebra Danio
Brachydanio rerio
Q32TF8
748
85439
I113
F
Y
L
E
D
D
T
I
Q
V
V
E
P
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624202
618
72361
H122
T
V
N
N
A
G
F
H
Q
G
K
L
I
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
71.1
N.A.
83.6
N.A.
N.A.
65.6
33.3
56.4
34
N.A.
N.A.
37
N.A.
N.A.
Protein Similarity:
100
99.8
99
76.4
N.A.
92.4
N.A.
N.A.
81.4
51.3
70
50.5
N.A.
N.A.
55.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
73.3
13.3
6.6
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
93.3
26.6
13.3
33.3
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
20
10
0
0
0
0
0
60
60
0
% D
% Glu:
0
0
0
20
0
0
0
0
0
0
0
80
0
20
0
% E
% Phe:
20
0
0
0
0
10
10
0
0
10
0
0
10
0
10
% F
% Gly:
0
0
0
0
0
20
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
60
20
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% K
% Leu:
0
0
20
0
0
0
0
0
0
0
80
10
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
50
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% P
% Gln:
0
0
0
50
0
0
0
0
30
0
0
0
0
10
0
% Q
% Arg:
60
0
60
0
0
0
0
0
0
0
0
10
0
10
10
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
60
% S
% Thr:
10
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% T
% Val:
0
20
0
10
50
0
0
0
0
30
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
10
0
0
0
0
60
60
50
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _