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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFHC1 All Species: 23.33
Human Site: Y37 Identified Species: 57.04
UniProt: Q5JVL4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JVL4 NP_060570.2 640 73990 Y37 T L S Y R N G Y A I V R R P T
Chimpanzee Pan troglodytes XP_001152433 640 73974 Y37 T L G Y R N G Y A I V R R P T
Rhesus Macaque Macaca mulatta XP_001107280 640 73892 Y37 T L G Y R N G Y A I V R R P T
Dog Lupus familis XP_532170 810 92443 Y206 T L S Y K N G Y A V V R R P T
Cat Felis silvestris
Mouse Mus musculus Q9D9T8 648 75123 Y37 T L N Y R N G Y A V V R R P T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510138 647 75030 Y37 T L G F R K G Y A F S R L P T
Chicken Gallus gallus Q32TG3 746 86643 D39 V A M L L A E D K P G I G G E
Frog Xenopus laevis NP_001086409 552 63835 T21 G N T Y R D P T K S A F H R S
Zebra Danio Brachydanio rerio Q32TF8 748 85439 K40 A M M V G T E K P G I G G D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624202 618 72361 S49 D S A H Y D P S L T Y G R V K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.9 71.1 N.A. 83.6 N.A. N.A. 65.6 33.3 56.4 34 N.A. N.A. 37 N.A. N.A.
Protein Similarity: 100 99.8 99 76.4 N.A. 92.4 N.A. N.A. 81.4 51.3 70 50.5 N.A. N.A. 55.1 N.A. N.A.
P-Site Identity: 100 93.3 93.3 86.6 N.A. 86.6 N.A. N.A. 60 0 13.3 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 N.A. N.A. 66.6 0 33.3 13.3 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 10 0 0 60 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 20 0 10 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 10 0 30 0 10 0 60 0 0 10 10 20 20 10 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 30 10 10 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 10 20 0 0 0 0 0 10 % K
% Leu: 0 60 0 10 10 0 0 0 10 0 0 0 10 0 10 % L
% Met: 0 10 20 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 50 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 20 0 10 10 0 0 0 60 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 60 0 0 0 0 0 0 60 60 10 0 % R
% Ser: 0 10 20 0 0 0 0 10 0 10 10 0 0 0 10 % S
% Thr: 60 0 10 0 0 10 0 10 0 10 0 0 0 0 60 % T
% Val: 10 0 0 10 0 0 0 0 0 20 50 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 60 10 0 0 60 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _