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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNAS
All Species:
9.09
Human Site:
S949
Identified Species:
18.18
UniProt:
Q5JWF2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.55
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JWF2
NP_536350.2
1037
111025
S949
E
K
V
L
A
G
K
S
K
I
E
D
Y
F
P
Chimpanzee
Pan troglodytes
XP_525370
1056
112593
S968
E
K
V
L
A
G
K
S
K
I
E
D
Y
F
P
Rhesus Macaque
Macaca mulatta
XP_001083581
1043
111280
S955
E
K
V
L
A
G
K
S
K
I
E
D
Y
F
P
Dog
Lupus familis
XP_860198
320
37536
E240
K
I
E
D
Y
F
P
E
Y
A
N
Y
T
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGK7
381
44290
E301
K
I
E
D
Y
F
P
E
Y
A
N
Y
T
V
P
Rat
Rattus norvegicus
P63095
394
45645
E314
K
I
E
D
Y
F
P
E
F
A
R
Y
T
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508838
309
36034
E229
K
I
E
D
Y
F
P
E
Y
V
N
Y
T
V
P
Chicken
Gallus gallus
XP_001231542
398
46270
E318
K
I
E
D
Y
F
P
E
F
A
R
Y
T
T
P
Frog
Xenopus laevis
P24799
379
44528
E299
K
I
E
D
Y
F
P
E
F
A
R
Y
T
T
P
Zebra Danio
Brachydanio rerio
XP_001335732
419
48693
E339
K
I
E
D
Y
F
P
E
F
A
R
Y
T
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20354
385
44980
K305
E
Y
F
S
E
F
N
K
Y
Q
T
P
I
D
T
Honey Bee
Apis mellifera
XP_623202
322
37719
A242
E
D
Y
F
P
D
F
A
R
Y
Q
T
P
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
94.5
25.4
N.A.
29.9
37.3
N.A.
25.2
33.5
33.2
35.3
N.A.
26.8
24.8
N.A.
N.A.
Protein Similarity:
100
97.6
95.4
29.2
N.A.
34
37.9
N.A.
27.9
36.8
35
38
N.A.
32.5
28.3
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
20
13.3
13.3
13.3
N.A.
6.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
0
9
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
59
0
9
0
0
0
0
0
25
0
9
9
% D
% Glu:
42
0
59
0
9
0
0
59
0
0
25
0
0
0
0
% E
% Phe:
0
0
9
9
0
67
9
0
34
0
0
0
0
25
0
% F
% Gly:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
59
0
0
0
0
0
0
0
25
0
0
9
0
0
% I
% Lys:
59
25
0
0
0
0
25
9
25
0
0
0
0
0
0
% K
% Leu:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
25
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
59
0
0
0
0
9
9
0
84
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
34
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
0
25
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
9
59
34
9
% T
% Val:
0
0
25
0
0
0
0
0
0
9
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
59
0
0
0
34
9
0
59
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _