KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY1
All Species:
14.85
Human Site:
Y498
Identified Species:
29.7
UniProt:
Q5JWR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JWR5
NP_055833.2
2465
277355
Y498
R
V
L
C
Q
E
T
Y
I
E
I
Q
T
E
H
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
N433
S
E
I
V
K
T
V
N
L
L
I
T
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
N421
S
E
I
V
K
T
V
N
L
L
I
T
S
L
S
Dog
Lupus familis
XP_532215
2465
276989
Y498
R
V
L
C
Q
E
T
Y
I
E
I
Q
T
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BL99
2399
269238
Y495
D
I
V
S
L
E
T
Y
I
E
I
Q
T
E
H
Rat
Rattus norvegicus
XP_236449
2462
276464
T497
M
R
V
L
C
Q
E
T
Y
I
E
I
Q
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512783
2941
328213
Y498
R
V
L
C
Q
E
T
Y
I
E
I
Q
T
E
H
Chicken
Gallus gallus
XP_419863
2466
277222
I499
V
L
C
Q
E
T
Y
I
E
I
Q
T
E
H
L
Frog
Xenopus laevis
Q642P2
2270
256829
Q405
D
A
L
G
T
Q
M
Q
L
S
Y
S
Q
N
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
S537
L
I
E
Q
S
G
G
S
S
S
D
E
K
I
T
Honey Bee
Apis mellifera
XP_395999
2434
273219
S521
K
V
Q
P
T
I
V
S
N
H
T
E
K
N
E
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
D508
F
L
W
T
F
L
G
D
W
Y
R
R
I
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.2
38.2
96.1
N.A.
89.2
93.2
N.A.
69.6
88.2
38.8
N.A.
N.A.
30.4
35.9
22
N.A.
Protein Similarity:
100
59.8
58.7
97.8
N.A.
92.2
96.5
N.A.
75.7
93.2
59.1
N.A.
N.A.
50.7
56.2
39.8
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
66.6
0
N.A.
100
0
6.6
N.A.
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
33.3
33.3
100
N.A.
80
13.3
N.A.
100
13.3
20
N.A.
N.A.
13.3
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
25
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
17
9
0
9
34
9
0
9
34
9
17
9
34
25
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
17
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
34
% H
% Ile:
0
17
17
0
0
9
0
9
34
17
50
9
9
9
0
% I
% Lys:
9
0
0
0
17
0
0
0
0
0
0
0
17
0
0
% K
% Leu:
9
17
34
9
9
9
0
0
25
17
0
0
0
17
9
% L
% Met:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
9
0
0
0
0
17
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
17
25
17
0
9
0
0
9
34
17
0
0
% Q
% Arg:
25
9
0
0
0
0
0
0
0
0
9
9
0
0
0
% R
% Ser:
17
0
0
9
9
0
0
17
9
17
0
9
17
0
17
% S
% Thr:
0
0
0
9
17
25
34
9
0
0
9
25
34
9
9
% T
% Val:
9
34
17
17
0
0
25
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
34
9
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _