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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKAPL All Species: 5.76
Human Site: T161 Identified Species: 12.67
UniProt: Q5M9Q1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5M9Q1 NP_001007532.1 402 46240 T161 V E D E E E V T H Q K S S S S
Chimpanzee Pan troglodytes XP_518308 399 45889 T161 V E D E E E V T H Q K S S S S
Rhesus Macaque Macaca mulatta XP_001099236 405 46727 M163 S E D E E E I M H Q K R S G S
Dog Lupus familis XP_549220 345 38782 K113 A S T S E E E K K K K K K S G
Cat Felis silvestris
Mouse Mus musculus Q9D0F4 415 47209 K168 V E D E E P K K S T T S A S S
Rat Rattus norvegicus Q4V7C9 415 47248 K168 V E D E E P K K S T T S A S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006437 361 41644 S129 A K S K S S S S D S S S E E E
Frog Xenopus laevis NP_001090505 326 37784 E94 A R R L K E R E R I G E L G A
Zebra Danio Brachydanio rerio NP_001003414 368 43163 P136 P D S D E H T P V E E D V K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB74 463 52929 K216 K K K K K K G K R K H K K S E
Honey Bee Apis mellifera XP_391898 247 28438 G15 R E Q I G L C G V D R I W G K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 88.4 58.4 N.A. 62.1 62.6 N.A. N.A. 62.4 51.4 54.4 N.A. 36 35 N.A. N.A.
Protein Similarity: 100 98.5 91.3 68.9 N.A. 72 71.5 N.A. N.A. 70.1 60.9 68.6 N.A. 49.2 47.2 N.A. N.A.
P-Site Identity: 100 100 66.6 26.6 N.A. 53.3 53.3 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 73.3 33.3 N.A. 60 60 N.A. N.A. 26.6 20 40 N.A. 40 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 0 0 0 0 0 0 0 0 0 0 19 0 10 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 46 10 0 0 0 0 10 10 0 10 0 0 0 % D
% Glu: 0 55 0 46 64 46 10 10 0 10 10 10 10 10 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 10 10 0 0 10 0 0 28 10 % G
% His: 0 0 0 0 0 10 0 0 28 0 10 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 10 0 0 10 0 10 0 0 0 % I
% Lys: 10 19 10 19 19 10 19 37 10 19 37 19 19 10 10 % K
% Leu: 0 0 0 10 0 10 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 10 0 0 0 0 19 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 28 0 0 0 0 0 % Q
% Arg: 10 10 10 0 0 0 10 0 19 0 10 10 0 0 0 % R
% Ser: 10 10 19 10 10 10 10 10 19 10 10 46 28 55 46 % S
% Thr: 0 0 10 0 0 0 10 19 0 19 19 0 0 0 0 % T
% Val: 37 0 0 0 0 0 19 0 19 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _