KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYC
All Species:
6.06
Human Site:
S227
Identified Species:
14.81
UniProt:
Q5MJ68
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ68
NP_001008778.1
293
33166
S227
G
L
P
Q
H
C
S
S
H
L
L
K
P
V
S
Chimpanzee
Pan troglodytes
XP_508546
355
39592
S289
G
L
P
Q
H
C
S
S
H
L
L
K
P
V
S
Rhesus Macaque
Macaca mulatta
XP_001118180
538
59269
R472
G
L
P
Q
H
C
S
R
H
Q
L
K
P
V
S
Dog
Lupus familis
XP_533235
197
22566
Q146
R
V
A
D
F
L
H
Q
R
D
K
L
W
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
R238
G
K
K
G
R
Y
V
R
L
G
L
S
S
S
S
Rat
Rattus norvegicus
Q8R496
312
36205
R238
G
K
K
G
R
Y
V
R
L
G
L
S
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
L238
G
K
K
R
C
V
E
L
G
L
S
S
S
S
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9YGL1
298
34536
S221
G
P
G
L
T
P
A
S
C
A
L
C
H
K
A
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
V230
A
K
T
S
A
L
P
V
P
R
P
S
S
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
P213
P
M
G
P
D
A
T
P
V
H
C
R
A
C
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
53.3
43.6
N.A.
33.8
34.9
N.A.
36
N.A.
41.6
34.8
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
81.9
53.3
48.8
N.A.
46.4
48.4
N.A.
47.2
N.A.
52.3
50.1
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
100
86.6
0
N.A.
20
20
N.A.
13.3
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
6.6
N.A.
20
20
N.A.
20
N.A.
33.3
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
10
10
0
0
10
0
0
10
20
10
% A
% Cys:
0
0
0
0
10
30
0
0
10
0
10
10
0
10
0
% C
% Asp:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
70
0
20
20
0
0
0
0
10
20
0
0
0
0
10
% G
% His:
0
0
0
0
30
0
10
0
30
10
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
40
30
0
0
0
0
0
0
0
10
30
0
10
0
% K
% Leu:
0
30
0
10
0
20
0
10
20
30
60
10
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
30
10
0
10
10
10
10
0
10
0
30
0
0
% P
% Gln:
0
0
0
30
0
0
0
10
0
10
0
0
0
0
10
% Q
% Arg:
10
0
0
10
20
0
0
30
10
10
0
10
0
0
10
% R
% Ser:
0
0
0
10
0
0
30
30
0
0
10
40
40
30
50
% S
% Thr:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
10
20
10
10
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _