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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYC
All Species:
13.33
Human Site:
S235
Identified Species:
32.59
UniProt:
Q5MJ68
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ68
NP_001008778.1
293
33166
S235
H
L
L
K
P
V
S
S
K
C
P
S
L
T
S
Chimpanzee
Pan troglodytes
XP_508546
355
39592
S297
H
L
L
K
P
V
S
S
K
C
P
S
L
T
S
Rhesus Macaque
Macaca mulatta
XP_001118180
538
59269
S480
H
Q
L
K
P
V
S
S
K
C
P
S
L
T
S
Dog
Lupus familis
XP_533235
197
22566
M154
R
D
K
L
W
A
R
M
G
F
R
A
M
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
S246
L
G
L
S
S
S
S
S
S
S
S
D
T
G
E
Rat
Rattus norvegicus
Q8R496
312
36205
S246
L
G
L
S
S
S
S
S
S
S
S
D
I
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
S246
G
L
S
S
S
S
Q
S
S
S
S
L
L
E
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9YGL1
298
34536
S229
C
A
L
C
H
K
A
S
V
C
D
S
G
G
V
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
P238
P
R
P
S
S
A
G
P
R
S
S
S
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
K221
V
H
C
R
A
C
E
K
A
E
R
Y
I
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
53.3
43.6
N.A.
33.8
34.9
N.A.
36
N.A.
41.6
34.8
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
81.9
53.3
48.8
N.A.
46.4
48.4
N.A.
47.2
N.A.
52.3
50.1
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
100
93.3
6.6
N.A.
20
20
N.A.
20
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
20
N.A.
20
26.6
N.A.
20
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
20
10
0
10
0
0
10
10
0
0
% A
% Cys:
10
0
10
10
0
10
0
0
0
40
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
10
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
20
0
0
0
0
10
0
10
0
0
0
10
20
0
% G
% His:
30
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
10
30
0
10
0
10
30
0
0
0
0
0
0
% K
% Leu:
20
30
60
10
0
0
0
0
0
0
0
10
40
10
20
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
10
0
30
0
0
10
0
0
30
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
10
0
0
10
0
10
0
20
0
0
0
0
% R
% Ser:
0
0
10
40
40
30
50
70
30
40
40
50
0
0
40
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
30
0
% T
% Val:
10
0
0
0
0
30
0
0
10
0
0
0
0
20
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _