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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYC
All Species:
9.09
Human Site:
Y18
Identified Species:
22.22
UniProt:
Q5MJ68
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ68
NP_001008778.1
293
33166
Y18
P
C
P
I
S
I
S
Y
E
M
S
D
S
Q
D
Chimpanzee
Pan troglodytes
XP_508546
355
39592
Y80
P
C
P
I
S
I
S
Y
E
M
S
D
S
Q
D
Rhesus Macaque
Macaca mulatta
XP_001118180
538
59269
Y263
T
C
P
I
S
I
S
Y
E
M
S
D
C
Q
D
Dog
Lupus familis
XP_533235
197
22566
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
V18
P
P
T
V
T
I
H
V
K
S
G
S
N
R
S
Rat
Rattus norvegicus
Q8R496
312
36205
V18
P
P
T
V
T
V
H
V
K
S
G
S
N
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
V17
T
P
T
L
S
V
L
V
K
S
A
A
S
R
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9YGL1
298
34536
K24
G
V
K
Q
I
I
A
K
G
H
P
N
T
R
V
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
H18
T
A
P
S
G
A
A
H
S
L
Q
I
R
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
T17
R
S
G
T
S
R
E
T
V
F
P
D
K
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
53.3
43.6
N.A.
33.8
34.9
N.A.
36
N.A.
41.6
34.8
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
81.9
53.3
48.8
N.A.
46.4
48.4
N.A.
47.2
N.A.
52.3
50.1
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
100
86.6
0
N.A.
13.3
6.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
0
N.A.
46.6
46.6
N.A.
46.6
N.A.
33.3
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
20
0
0
0
10
10
0
0
0
% A
% Cys:
0
30
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
30
% D
% Glu:
0
0
0
0
0
0
10
0
30
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
10
0
10
0
0
0
10
0
20
0
0
0
10
% G
% His:
0
0
0
0
0
0
20
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
30
10
50
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
30
0
0
0
10
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
20
0
0
% N
% Pro:
40
30
40
0
0
0
0
0
0
0
20
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
10
0
0
30
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
0
10
50
0
% R
% Ser:
0
10
0
10
50
0
30
0
10
30
30
20
30
0
30
% S
% Thr:
30
0
30
10
20
0
0
10
0
0
0
0
10
0
10
% T
% Val:
0
10
0
20
0
20
0
30
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _