KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYA
All Species:
13.03
Human Site:
S22
Identified Species:
31.85
UniProt:
Q5MJ70
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ70
NP_001008779.1
313
36463
S22
T
V
Y
V
K
S
G
S
N
R
S
H
Q
P
K
Chimpanzee
Pan troglodytes
XP_515374
225
26070
Rhesus Macaque
Macaca mulatta
XP_001102674
313
36653
S22
T
V
Y
V
K
S
G
S
N
R
S
H
Q
P
K
Dog
Lupus familis
XP_533235
197
22566
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
S22
T
I
H
V
K
S
G
S
N
R
S
H
Q
T
R
Rat
Rattus norvegicus
Q8R496
312
36205
S22
T
V
H
V
K
S
G
S
N
R
S
H
Q
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
A21
S
V
L
V
K
S
A
A
S
R
S
H
P
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
I22
G
S
G
V
K
Q
V
I
G
K
G
H
P
H
A
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
R23
A
A
H
S
L
Q
I
R
R
G
P
R
K
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
97.4
28.4
N.A.
83.3
85.9
N.A.
69.3
N.A.
39.6
49.8
N.A.
N.A.
N.A.
N.A.
42.8
Protein Similarity:
100
71.8
98.7
38.6
N.A.
90
91
N.A.
80.8
N.A.
55.9
64.8
N.A.
N.A.
N.A.
N.A.
59.4
P-Site Identity:
100
0
100
0
N.A.
73.3
80
N.A.
60
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
0
N.A.
93.3
93.3
N.A.
80
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
40
0
10
10
10
0
0
0
0
% G
% His:
0
0
30
0
0
0
0
0
0
0
0
60
0
10
0
% H
% Ile:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
60
0
0
0
0
10
0
0
10
0
30
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
20
30
0
% P
% Gln:
0
0
0
0
0
20
0
0
0
0
0
0
40
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
50
0
10
0
0
30
% R
% Ser:
10
10
0
10
0
50
0
40
10
0
50
0
0
0
0
% S
% Thr:
40
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% T
% Val:
0
40
0
60
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _