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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYA
All Species:
13.03
Human Site:
S246
Identified Species:
31.85
UniProt:
Q5MJ70
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ70
NP_001008779.1
313
36463
S246
R
L
G
L
S
S
S
S
S
L
S
S
H
T
A
Chimpanzee
Pan troglodytes
XP_515374
225
26070
S159
L
G
L
S
S
S
S
S
L
S
S
H
T
A
G
Rhesus Macaque
Macaca mulatta
XP_001102674
313
36653
S246
R
L
G
L
S
S
S
S
S
L
S
S
H
T
S
Dog
Lupus familis
XP_533235
197
22566
A131
K
C
V
I
F
L
W
A
L
G
K
D
W
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
S243
Y
V
R
L
G
L
S
S
S
S
S
S
S
S
D
Rat
Rattus norvegicus
Q8R496
312
36205
S245
R
L
G
L
S
S
S
S
S
S
S
S
D
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
Q245
L
G
L
S
S
S
S
Q
S
S
S
S
L
L
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
T223
G
L
T
P
A
S
C
T
L
C
H
K
A
G
V
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
L221
A
S
P
E
P
C
F
L
C
A
K
T
S
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
D200
R
K
Y
P
D
Y
D
D
D
N
E
A
I
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
97.4
28.4
N.A.
83.3
85.9
N.A.
69.3
N.A.
39.6
49.8
N.A.
N.A.
N.A.
N.A.
42.8
Protein Similarity:
100
71.8
98.7
38.6
N.A.
90
91
N.A.
80.8
N.A.
55.9
64.8
N.A.
N.A.
N.A.
N.A.
59.4
P-Site Identity:
100
33.3
93.3
0
N.A.
40
73.3
N.A.
40
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
20
N.A.
53.3
73.3
N.A.
40
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
10
0
10
0
10
10
20
10
% A
% Cys:
0
10
0
0
0
10
10
0
10
10
0
0
0
0
10
% C
% Asp:
0
0
0
0
10
0
10
10
10
0
0
10
10
0
10
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
30
0
10
0
0
0
0
10
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
10
20
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
10
10
0
0
0
0
0
0
0
0
20
10
0
0
0
% K
% Leu:
20
40
20
40
0
20
0
10
30
20
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
20
10
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
40
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
20
50
60
60
50
50
40
60
50
20
10
10
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
10
10
20
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _